Lurasidone Intermediate (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione[CAS:14805-29-9] (1R,2R)-1,2-Cyclohexanedimethanol[CAS:65376-05-8] Lurasidone Hydrochloride [CAS:367514-88-3] HANGZHOU THINK CHEMICAL CO., LTD. (THINKC
Cas:14805-29-9
Min.Order:1 Kilogram
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inquiryProduct Description Product website: http://www.finerchem.com/pro01en/id/254.html Product Name (3aR,4S,7R,7aS)-rel-Hexahydro-4,7-methano-1H-isoindole-1,3(2H)-dione
Cas:14805-29-9
Min.Order:1 Gram
FOB Price: $24.0
Type:Lab/Research institutions
inquiryAs a leading manufacturer and supplier of chemicals in China, DayangChem not only supply popular chemicals, but also DayangChem's R&D center offer custom synthesis services. DayangChem can provide different quantities of custom synthesis ch
Cas:14805-29-9
Min.Order:1 Kilogram
FOB Price: $3.0
Type:Lab/Research institutions
inquiryhebei yanxi chemical co., LTD who registered capital of 10 million yuan, nearly to $2 million, we have a pharmaceutical raw materials factory production of pharmaceutical raw materials, and a reagent r&d center, and we do research and developm
Cas:14805-29-9
Min.Order:1 Metric Ton
FOB Price: $1.0 / 3.0
Type:Manufacturers
inquiryThe above product is Ality Chemical's strong item with best price, good quality and fast supply. Ality Chemical has been focusing on the research and production of this field for over 14 years. At the same time, we are always committed to providi
Cas:14805-29-9
Min.Order:1
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Type:Other
inquiryCangzhou Enke Pharma Tech Co.,ltd. is located in Cangzhou City, Hebei province ,where is a famous petroleum chemical industry city in China. Enke Pharma a high-tech enterprise ,and we are dedicated to developing and manufacturing new api, intermedi
Cas:14805-29-9
Min.Order:1 Kilogram
FOB Price: $1.0
Type:Manufacturers
inquiry1. made in GMP plant, commerially 2. Normal Stock: 500kgs 3. Audit accepted. Related documents are available to offer and audited by many clients, such as Lupin, MSN, Dr reddy etc 4. Chromatographic Purity (HPLC): not less than 99
Cas:14805-29-9
Min.Order:0 Metric Ton
Negotiable
Type:Manufacturers
inquiryOur main production base is located in Xuzhou industry park. We are certified both to the ISO 9001 and ISO 14001 Standards, have a safety management system in place.Our R&D team masters core technology for process-design of target building block
Cas:14805-29-9
Min.Order:5 Kiloliter
FOB Price: $1.2 / 5.0
Type:Manufacturers
inquiryOur company was built in 2009 with an ISO certificate.In the past 5 years, we have grown up as a famous fine chemicals supplier in China and we had established stable business relationships with Samsung,LG,Merck,Thermo Fisher Scientific and so on.O
Cas:14805-29-9
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryLIDE PHARMACEUTICALS LIMITED is a professional chemicals and APIs leading manufacturer in China. Our core business line covers APIs, Intermediates, Herb extract, etc.
Cas:14805-29-9
Min.Order:1 Kilogram
FOB Price: $0.9 / 1.0
Type:Lab/Research institutions
inquiryWhy is SINOWAY: 1) Specialized in pharmaceutical and healthcare industrial for 34 years. 2) ISO 9001:2015 & SGS audited supplier . 3) Accept various payment terms : T.T 30-60 days. 4) We have warehouse in USA with quickly shipment . 5) We c
Cas:14805-29-9
Min.Order:25 Kilogram
FOB Price: $100.0
Type:Trading Company
inquiryWITH US,YOUR MONEY IN SAFE,YOUR BUSINESS IN SAFE 1)Quick Response Within 12 hours; 2)Quality Guarantee: All products are strictly tested by our QC, confirmed by QA and approved by third party lab in China, USA, Canada, Germany, UK, Italy, France et
Cas:14805-29-9
Min.Order:1 Kilogram
FOB Price: $139.0 / 210.0
Type:Trading Company
inquiryProduct Name: (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione Synonyms: (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione;Nsc238001;2,3-Norbornanedicarboximide, exo- (8CI);(3aR,4S,7R,7aS)-rel-He
Cas:14805-29-9
Min.Order:5 Metric Ton
FOB Price: $1.0 / 2.0
Type:Other
inquiryOur Advantage Rich Experience Our products are sold all over Europe,North&South America, Sino-East, Asia and pacific area as well as Africa,we establish long term. Quality service Company cooperates with research institutes. We strictly con
Cas:14805-29-9
Min.Order:1 Kilogram
FOB Price: $15.0 / 50.0
Type:Trading Company
inquiryAdvantages: Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best s
Cas:14805-29-9
Min.Order:10 Gram
Negotiable
Type:Other
inquiry1.In No Less 10 years exporting experience. you can 100% received goods 2.Lower Price with higher quality 3,Free sample 4,We are sincerely responsible for the "product quality" and "After Service" Upbio is Specializ
Cas:14805-29-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryOur company has been in existence for 10 years since its establishment. We have our own unique team. The company integrates independent research and development, production and sales. We have established famous brands at home and abroad. At present
Cas:14805-29-9
Min.Order:1 Kilogram
FOB Price: $49.0 / 121.0
Type:Trading Company
inquiryBeluga chemical professional supply (3aR,4S,7R,7aS)-hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione CAS 14805-29-9 1. Beluga Chemical has a professional RESEARCH and development team and strong technical force to ensure technical support and resea
Cas:14805-29-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryHello, dear friend! I'm Hansen and Allen from China. Welcome to my lookchem mall! The following is a brief introduction of our company's products and services. If you are interested in our products, please contact us by emai
Cas:14805-29-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryHenan Wentao Chemical Product Co.,Ltd is Located in Zhengzhou High-tech Development Zone with import and export license, We passed ISO 9001:2008 as well, Henan Wentao has developed more than 1000 compounds, which are widely used in the fields of prod
Cas:14805-29-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryAppearance:white powder without visible impurities Storage:Store in a cool,dry place and keep away from direct strong light Package:As customer request Application:Used for research and industrial manufacture. Transportation:By
Cas:14805-29-9
Min.Order:100 Gram
Negotiable
Type:Lab/Research institutions
inquiryCompany Introduction 1. Established in 2005, with two independent business divisions: Fine chemicals division; Pharmaceutical division. 2. Main product: Optical brightener Textile auxiliary Dye stuff Pigments
Cas:14805-29-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryA substitute for perfluorooctanoic acid, mainly used as a surfactant, dispersant, additive, etc Appearance:White solid or Colorless liquid Purity:99.3 % We will ship the goods in a timely manner as required We can provide relevant documents acc
Cas:14805-29-9
Min.Order:4 Kilogram
Negotiable
Type:Lab/Research institutions
inquiryJ&H CHEM R&D center can offer custom synthesis according to the contract research and development services for the fine chemicals, pharmaceutical, biotechnique and some of the other chemicals. J&H CHEM has some Manufacturing base in Jia
Cas:14805-29-9
Min.Order:0
Negotiable
Type:Lab/Research institutions
inquiryMassive Chemical is certified with ISO9001 and ISO14001 manufacturer for this product. We will offer all documents as requirement for the materials which includes, Certificate of Analysis, Material Safety Data Sheet, and Method of Analysis and
Cas:14805-29-9
Min.Order:1 Gram
FOB Price: $1.0
Type:Lab/Research institutions
inquiryZibo Hangyu Biotechnology Development Co., Ltd is a leading manufacturer and supplier of chemicals in China. We develop produce and distribute high quality pharmaceuticals, intermediates, special chemicals and OLED intermediates and other fine chemi
Cas:14805-29-9
Min.Order:10 Gram
FOB Price: $100.0
Type:Lab/Research institutions
inquiryProduct name: (3aR,4S,7R,7aS)-4,7-Methano-1H-Isoindole-1,3(2H)-Dione CAS No.: 14805-29-9 Molecule Formula:C9H11NO2 Molecule Weight:165.19 Purity: 98.0% Package: 25kg/drum Description:White powder Manufacture Standards:Enterprise Stand
Cas:14805-29-9
Min.Order:1 Kilogram
Negotiable
Type:Trading Company
inquiryProduct Details Grade: pharmaceutical grade Purity:99%+ ProductionCapacity: 1000 Kilogram/Month Scope of use: For scientific research only(The product must be used legally) Our Advantage 1. Best quality with competitive price. 2. Quick shipping,
Cas:14805-29-9
Min.Order:1 Kilogram
Negotiable
Type:Lab/Research institutions
inquiry(3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione Basic information Product Name: (3aR,4S,7R,7aS) 4,7-Methano-1H-isoindole-1,3(2H)-dione Synonyms: 4,7-Methano-1H-isoindole-1,3(2H)-dione, hexahydro-, (3aR,4S,7R,7aS)-rel-;(3aR,4S,7R,7aS)-He
Cas:14805-29-9
Min.Order:1 Gram
Negotiable
Type:Lab/Research institutions
inquiryfactory?direct?saleAppearance:White Powder Storage:Store In Dry, Cool And Ventilated Place Package:25kg/drum, also according to the clients requirement Application:It is widely used as a thickener, emulsifier and stabilizer Transportation:By Sea Or B
Cas:14805-29-9
Min.Order:1 Kilogram
FOB Price: $18.0 / 20.0
Type:Trading Company
inquiry(1R,2S,6R,7S)-4-azatricyclo[5.2.1.0(2,6)]dec-8-ene-3,5-dione
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With palladium 10% on activated carbon; hydrogen In methanol Autoclave; Industrial scale; | 91.4% |
exo-bicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With ammonium hydroxide In tetrahydrofuran at 190℃; for 2h; | 80.5% |
Multi-step reaction with 2 steps 1: triethylamine / toluene / Reflux 2: pyridine / 0 - 20 °C View Scheme | |
Stage #1: exo-bicyclo[2.2.1]heptane-2,3-dicarboxylic anhydride In tetrahydrofuran at 25 - 35℃; for 0.166667h; Stage #2: With ammonia In tetrahydrofuran; water at 0 - 35℃; |
(1R,2R,6S,7S)-4-oxa-tricyclo[5.2.1.02,6]dec-8-ene-3,5-dione
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 95.9 percent / H2 / 10percent Pd/C / H2O; tetrahydrofuran / 1.5 h / Ambient temperature 2: 80.5 percent / 7percent aq. NH3 / tetrahydrofuran / 2 h / 190 °C View Scheme | |
Multi-step reaction with 2 steps 1: 95.9 percent / H2 / 10percent Pd-C/ 50percent H2O / tetrahydrofuran / 1.5 h / Ambient temperature 2: 80.5 percent / 7percent aq. NH3 / tetrahydrofuran / 2 h / 190 °C View Scheme | |
Multi-step reaction with 2 steps 1.1: palladium on activated charcoal; hydrogen / 25 - 35 °C / 3750.38 Torr / Inert atmosphere; Autoclave 2.1: tetrahydrofuran / 0.17 h / 25 - 35 °C 2.2: 0 - 35 °C View Scheme |
methanesulfonyl chloride
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Stage #1: (3aR,4S,7R,7aS)-2-(((1R,2R)-2-(hydroxymethyl)cyclohexyl)methy)hexahydro-1H-4,7-methanoisoindole-1,3(2H)-dione; methanesulfonyl chloride With pyridine at 0 - 20℃; Stage #2: With hydrogenchloride In water |
cyclopenta-1,3-diene
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1.1: 1 h / 200 °C 2.1: palladium on activated charcoal; hydrogen / 25 - 35 °C / 3750.38 Torr / Inert atmosphere; Autoclave 3.1: tetrahydrofuran / 0.17 h / 25 - 35 °C 3.2: 0 - 35 °C View Scheme |
3,6-endomethylene-1,2,3,6-tetrahydrophthalic anhydride
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: ammonium acetate / 135 °C / Industrial scale 2: hydrogen; palladium 10% on activated carbon / methanol / Autoclave; Industrial scale View Scheme |
1,5-dibromo-pentane
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
N-(4-Bromopentyl)bicyclo<2.2.1>heptane-2,3-di-exo-carboximide
Conditions | Yield |
---|---|
With potassium carbonate In acetone Heating; | 100% |
(1R,2R)-(-)-trans-cyclohexane-1,2-diylbis(methylene)dimethanesulfonate
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate In isopropyl alcohol for 4h; | 99% |
(3aR,7aR)-4’-(benzo[d]isothiazol-3-yl)octahydrospiro[isoindole-2,1’-piperazin]-2-ium methanesulfonate
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
(3aR,4S,7R,7aS)-2-[((1R,2R)-2-{[4-(l1,2-benzisothiazol-3-yl)piperazin-1-yl]methyl}cyclohexyl)methyl]hexahydro-1H-4,7-methanisoindol-1,3-dione hydrochloride
Conditions | Yield |
---|---|
Stage #1: (3aR,7aR)-4’-(benzo[d]isothiazol-3-yl)octahydrospiro[isoindole-2,1’-piperazin]-2-ium methanesulfonate; (3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione With potassium carbonate In toluene at 105℃; for 15h; Industrial scale; Stage #2: With hydrogenchloride In isopropyl alcohol Industrial scale; | 98.3% |
Multi-step reaction with 2 steps 1.1: potassium carbonate; dibenzo-18-crown-6 / 5,5-dimethyl-1,3-cyclohexadiene / 3 h 2.1: methanol / 0.17 h / 60 - 65 °C 2.2: 1 h / 60 - 65 °C View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate In water for 10h; Reflux; | 95% |
4-chlorobutyl bromide
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 0 - 20℃; | 95% |
(3aR,7aR)-4’-(benzo[d]isothiazol-3-yl)octahydrospiro[isoindole-2,1’-piperazin]-2-ium methanesulfonate
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate In water; toluene for 8h; Product distribution / selectivity; Reflux; | 94.3% |
With tetra(n-butyl)ammonium hydrogensulfate; potassium carbonate In water for 3h; Product distribution / selectivity; Reflux; | 94.3% |
With potassium carbonate In N,N-dimethyl-formamide at 120℃; for 36h; Temperature; | 91.8% |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
propargyl bromide
N-Propargylbicyclo<2.2.1>heptane-2,3-di-exo-carboximide
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 1h; Heating; | 91% |
1,4-dibromo-butane
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
(1R,2S,3R,4S)-N-(4-bromobutyl)-2,3-bicyclo<2.2.1>heptanedicarboximide
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 7h; Heating; | 90.2% |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
1-chloro-3,4-epoxybutane
(1R,2S,3R,4S)-N-(3,4-epoxybutyl)-2,3-bicyclo<2.2.1>heptanedicarboxamide
Conditions | Yield |
---|---|
With potassium carbonate In acetone for 2h; Heating; | 90.1% |
Z-1,4-dichlorobutene
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
N-(4-Chloro-2-cis-butenyl)bicyclo<2.2.1>heptane-2,3-di-exo-carboximide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 90 - 100℃; | 90% |
trans-1,4-dichlorobut-2-ene
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
N-(4-Chloro-2-trans-butenyl)bicyclo<2.2.1>heptane-2,3-di-exo-carboximide
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 90 - 100℃; for 2h; | 88.7% |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With dibenzo-18-crown-6; potassium carbonate In xylene for 10h; Heating; | A 17.2% B 82.7% |
(3aR,7aR)-2,2-bis(2-hydroxyethyl)octahydro-1H-isoindolium mesylate
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 120℃; for 16h; | 80% |
8-(2-quinolinyl)-8-aza-5-azoniaspiro<4.5>decane bromide
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate; 18-crown-6 ether In xylene for 6h; Heating; | 76% |
4-(3,4-Epoxybutyl)-1-(2-pyrimidinyl)piperazine
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
(1R*,2S*,3R*,4S*)-N-<2-Hydroxy-4-<4-(2-pyrimidinyl)-1-piperazinyl>butyl>-2,3-bicyclo<2.2.1>heptanedicarboximide
Conditions | Yield |
---|---|
With potassium carbonate In butan-1-ol for 6h; Heating; | 59% |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
With potassium carbonate In butan-1-ol for 9h; Heating; | 47.7% |
Conditions | Yield |
---|---|
With potassium carbonate In N,N-dimethyl-formamide at 133℃; for 2h; Molecular sieve; | 42% |
1,4-dibromo-butane
N-(2-pyridinyl)piperazine
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
tandospirone
Conditions | Yield |
---|---|
With potassium carbonate; benzyltriethylammonium bromide 1.) toluene, reflux, 4 h, 2.) reflux, 5 h; Yield given. Multistep reaction; |
8-(2-Pyrimidinyl)-8-aza-5-azoniaspiro[4.5]decane Bromide
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
tandospirone
Conditions | Yield |
---|---|
With potassium carbonate; 18-crown-6 ether In xylene for 6h; Heating; |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
(1S,2R,6S,7R)-4-{4-[4-(3-Chloro-pyridin-2-yl)-piperazin-1-yl]-butyl}-4-aza-tricyclo[5.2.1.02,6]decane-3,5-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: K2CO3, KI / acetonitrile / 8 h / Heating View Scheme | |
Multi-step reaction with 2 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: 34 percent / K2CO3, KI / dimethylformamide / 90 °C View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 3 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: K2CO3, KI / acetonitrile / 8 h / Heating 3: 63 percent / NaBH4, 0.1percent aq. NaOH / propan-2-ol / 2 h / Heating View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90.1 percent / K2CO3 / acetone / 2 h / Heating 2: 80.7 percent / butan-1-ol / 12 h / Heating View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: K2CO3, KI / acetonitrile / 8 h / Heating View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: 62.5 percent / K2CO3, KI / acetonitrile / 8 h / Heating View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
(1R,2S,3R,4S)-N-<4-<4-(1,2-benzisothiazol-3-yl)-1-piperazinyl>butyl>-2,3-bicyclo<2.2.1>heptanedicarboximide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: K2CO3, KI / acetonitrile / 8 h / Heating View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: 66.4 percent / K2CO3, KI / acetonitrile / 8 h / Heating View Scheme |
(3aR,4S,7R,7aS)‑4,7‑methylene‑1H‑isoindole‑1,3(2H)-dione
N-<4-(3-Methyl-1-piperazinyl)butyl>bicyclo<2.2.1>heptane-2,3-di-exo-carboximide
Conditions | Yield |
---|---|
Multi-step reaction with 2 steps 1: 90.2 percent / K2CO3 / acetone / 7 h / Heating 2: 100 percent / ethanol / Ambient temperature View Scheme |
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