1000025-50-2Relevant articles and documents
Design and synthesis of substituted pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors
Warshakoon, Namal C.,Wu, Shengde,Boyer, Angelique,Kawamoto, Richard,Sheville, Justin,Bhatt, Ritu Tiku,Renock, Sean,Xu, Kevin,Pokross, Matthew,Zhou, Songtao,Walter, Richard,Mekel, Marlene,Evdokimov, Artem G.,East, Stephen
, p. 5616 - 5620 (2007/10/03)
Structure-guided de novo drug design led to the identification of a novel series of substituted pyridine derivatives as HIF-1α prolyl hydroxylase inhibitors. Pyridine carboxyamide derivatives bearing a substituted aryl group at the 5-position of the pyrid