100278-74-8

Basic information

• Product Name: Phenol, 5-chloro-4-methyl-2-nitro-
• CAS NO: 100278-74-8
• Molecular Formula: C7H6ClNO3
• Molecular Weight: 187.583
• Mol File: 100278-74-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Phenol, 5-chloro-4-methyl-2-nitro-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 5-chloro-4-methyl-2-nitro-(100278-74-8)
• EPA Substance Registry System: Phenol, 5-chloro-4-methyl-2-nitro-(100278-74-8)

Safety Data

• Hazardous Substances Data: 100278-74-8(Hazardous Substances Data)

Usage

General Description

Phenol, 5-chloro-4-methyl-2-nitro- is a chemical compound with the molecular formula C7H6ClNO3. It is a nitrophenol derivative and is a pale yellow crystalline solid. Phenol, 5-chloro-4-methyl-2-nitro- is used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals. It is also used as a chemical intermediate in the production of dyes, pigments, and other organic compounds. Phenol, 5-chloro-4-methyl-2-nitro- is known to have moderate acute toxicity and has the potential to cause irritation to the skin, eyes, and respiratory system. It is important to handle this chemical with care and follow proper safety precautions when working with it.

Upstream product

• 98-59-9 p-toluenesulfonyl chloride 
• 42413-03-6 3-chloro-4-methylbenzenesulfonyl chloride 
• 54788-38-4 2-chloro-4-methoxy-1-methylbenzene 
• 56180-49-5 4-chloro-4-methylcyclohexa-2,5-dien-1-one 
• 861560-18-1 2-chloro-5-nitro-toluene-4-sulfonyl chloride 
• 112251-96-4 3-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone 
• 615-62-3 3-chloro-4-methylphenol 
• 95-74-9 3-chloro-p-toluidine 

Downstream Products

• 1268818-21-8 2-(5-chloro-4-methyl-2-nitrophenoxy)acetonitrile 
• 1185320-25-5 7-chloro-6-methyl-2H-benzo[b][1,4]oxazin-3(4H)-one 
• 1015485-42-3 5-chloro-4-methyl-2-nitrophenyltrifluoromethanesulfonate 
• 100777-46-6 1-chloro-5-methoxy-2-methyl-4-nitrobenzene 

Relevant articles and documents

ANTIBIOTIC COMPOUNDS

The present invention relates to antibiotic compounds of formula (I), to compositions containing these compounds and to methods of treating bacterial diseases and infections using the compounds. The compounds find application in the treatment of infection with, and diseases caused by, Gram-positive and/or Gram-negative bacteria, and in particular in the treatment of infection with, and diseases caused by, Neisseria gonorrhoeae.

ipso NITRATION. XXIX. NITRATION OF SUBSTITUTED 4-METHYLANISOLES AND PHENOLS

Nitration of 2-chloro-4-methylanisole (1a) in acetic anhydride gives (Z)-4-chloro-3-methoxy-6-methyl-6-nitrocyclohexa-2,4-dienyl acetate (2a), 2-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone (3a), and 2-chloro-4-methyl-6-nitroanisole (4a).Similarly 2-bromo-4-methylanisole (1b) gives (Z)-4-bromo-3-methoxy-6-methyl-6-nitrocyclohexa-2,4-dienyl acetate (2b), 2-bromo-4-methyl-4-nitrocyclohexa-2,5-dienone (3b), and 2-bromo-4-methyl-6-nitroanisole (4b), whereas 4-methyl-2-nitro-anisole (1c) gives (Z)-3-methoxy-6-methyl-4,6-dinitrocyclohexa-2,4-dienyl acetate (2c), (Z)-3-methoxy-6-methyl-2,6-dinitrocyclohexa-2,4-dienyl acetate (7), and 4-methyl-2,6-dinitroanisole (4c).Nitration of 3-chloro-4-methylanisole (9a) gives 3-chloro-4-methyl-4-nitrocyclohexa-2,5-dienone (10a), 3-chloro-4-methyl-2-nitro anisole (11a), and 5-chloro-4-methyl-2-nitroanisole (12a), and 4-methyl-3-nitroanisole (9c) gives (Z)-3-methoxy-6-methyl-5,6-dinitrocyclohexa-2,4-dienyl acetate (13), 4-methyl-2,3-dinitroanisole (11c), and 4-methyl-2,5-dinitroanisole (12c).Nitration of 2-chloro-4-methylphenol (14) in chloroform gives 3a and 2-chloro-4-methyl-6-nitrophenol (5a), and 3-chloro-4-methylphenol (15) gives dienone 10a, 3-chloro-4-methyl-2-nitrophenol (16), and 5-chloro-4-methyl-2-nitrophenol (17).

Miticidal 2-(2-methyl-2,3-dihydro-benzofuran-7-yl)hydrazinecarboxylic acid esters

Certain miticidal 2-(2-alkyl-2,3-dihydro-benzofuran-7-yl)-hydrazinecarboxylic acid esters.