1003577-87-4Relevant articles and documents
Novel acyl coenzyme A (CoA): Diacylglycerol acyltransferase-1 inhibitors: Synthesis and biological activities of diacylethylenediamine derivatives
Nakada, Yoshihisa,Aicher, Thomas D.,Huerou, Yvan Le,Turner, Timothy,Pratt, Scott A.,Gonzales, Stephen S.,Boyd, Steve A.,Miki, Hiroshi,Yamamoto, Toshihiro,Yamaguchi, Hiroshi,Kato, Koki,Kitamura, Shuji
experimental part, p. 2785 - 2795 (2010/07/04)
A series of diacylethylenediamine derivatives were synthesized and evaluated for their inhibitory activity against DGAT-1 and pharmacokinetic profile to discover new small molecule DGAT-1 inhibitors. Among the compounds, N-[2-({[1-phenyl-3-(trifluoromethy