100445-98-5 Usage
Description
(Tetrahydro-pyrrolizin-7a-yl)-acetyl chloride is a chemical compound characterized by the molecular formula C10H14ClNO. It is an acetyl chloride derivative of the tetrahydro-pyrrolizin-7a-yl group, which positions it as a potentially significant building block for the synthesis of a wide array of pharmaceuticals and organic compounds. (Tetrahydro-pyrrolizin-7a-yl)-acetyl chloride's structure indicates its utility in organic chemistry as a reagent, particularly in the acylation of other compounds. Additionally, the acetyl chloride group endows it with suitability for reactions involving acetylation. Its potential pharmacological properties render it a compound of interest for further research and development.
Uses
Used in Pharmaceutical Synthesis:
(Tetrahydro-pyrrolizin-7a-yl)-acetyl chloride is used as a key intermediate in the pharmaceutical industry for the synthesis of various drugs. Its unique structure allows for the creation of new molecules with potential therapeutic applications.
Used in Organic Chemistry:
In the field of organic chemistry, (Tetrahydro-pyrrolizin-7a-yl)-acetyl chloride is used as a reagent for the acylation of other compounds. Its acetyl chloride group facilitates reactions that can lead to the formation of new organic molecules with diverse properties and potential applications.
Used in Research and Development:
(Tetrahydro-pyrrolizin-7a-yl)-acetyl chloride is also utilized in research and development settings to explore its potential pharmacological properties. Scientists are interested in its capacity to contribute to the development of new drugs and therapies, as well as its possible applications in other areas of chemistry and materials science.
Used in Chemical Synthesis:
(Tetrahydro-pyrrolizin-7a-yl)-acetyl chloride is employed in the chemical synthesis industry as a versatile building block for creating a range of organic compounds. Its ability to participate in acylation reactions makes it a valuable component in the development of new chemical products with various applications.
Check Digit Verification of cas no
The CAS Registry Mumber 100445-98-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,0,4,4 and 5 respectively; the second part has 2 digits, 9 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 100445-98:
(8*1)+(7*0)+(6*0)+(5*4)+(4*4)+(3*5)+(2*9)+(1*8)=85
85 % 10 = 5
So 100445-98-5 is a valid CAS Registry Number.
100445-98-5Relevant articles and documents
Synthesis and muscarinic activity of a series of quinolines and naphthalenes with a 1-azabicyclo[3.3.0]octane moiety
Suzuki, Tomoo,Usui, Toshinao,Oka, Mitsuru,Suzuki, Tsunemasa,Kataoka, Tadashi
, p. 1265 - 1273 (2007/10/03)
In order to discover a medicine effective against Alzheimer's disease, we synthesized a series of quinoline derivatives having a characteristic 1- azabicyclo[3.3.0]octane amine ring, and performed pharmacological evaluation of them. Acetylcholine esterase inhibitory activities of these derivatives were unexpectedly weak. Tests for central nervous muscarinic cholinergic receptor binding affinity indicated that these compounds had higher affinities to muscarinic M1 receptors than to M2 receptors. A series of naphthalene derivatives substituted with the 1-azabicyclo[3.3.0]octane ring were also synthesized and muscarinic M1 and M2 receptor binding affinity determined. These compounds had much higher affinity for M1 receptors than the quinoline derivatives, and 1-[N-(1-azabicyclo[3.3.0]octan-5-yl)methyl-N- methylamino]-4-nitronaphthalene showed the highest affinity and selectivity. The ability of this compound to improve cognitive function was assessed using the passive avoidance test in scopolamine-induced mice.
