100765-38-6

Basic information

• Product Name: (E)-1-(4-chlorophenyl)oct-1-en-3-one
• Synonyms: (E)-1-(4-chlorophenyl)oct-1-en-3-one
• CAS NO: 100765-38-6
• Molecular Weight: 236.741
• Mol File: 100765-38-6.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (E)-1-(4-chlorophenyl)oct-1-en-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-chlorophenyl)oct-1-en-3-one(100765-38-6)
• EPA Substance Registry System: (E)-1-(4-chlorophenyl)oct-1-en-3-one(100765-38-6)

Safety Data

• Hazardous Substances Data: 100765-38-6(Hazardous Substances Data)

Upstream product

• 16339-93-8 1-bromoheptan-2-one 
• 104-88-1 4-chlorobenzaldehyde 
• 121077-69-8 (2-Oxoheptyl)triphenylarsonium bromide 
• 110-43-0 n-pentyl methyl ketone 

Downstream Products

• 1428261-46-4 C₂₀H₁₉Cl₃N₂ 
• 100765-44-4 1-(4-chlorophenyl)-3-octanone 

Relevant articles and documents

Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21

Searching for novel antiobesity agents, a series of cannabinoid LH21 and of Rimonabant-fatty acid amide analogues have been prepared. Synthesis of pyrazoles 2a-2c was achieved by a two steps simple methodology via α,β-unsaturated ketones. Carboxamides 8a-8h were obtained in good yields from esters 7a-7c by a one-pot procedure which takes place under mild conditions. New compounds have been evaluated in vivo as anorectic agents. Some of them showed interesting properties reducing food intake in rats by a mechanism which does not involve the endocannabinoid system.

An Improved Procedure for the Claisen-Shmidt Reaction

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