1010128-92-3

Basic information

• Product Name: methyl 3-[(diphenylphosphoryl)(methyl)amino]-3-phenylpropanoate
• Synonyms: methyl 3-[(diphenylphosphoryl)(methyl)amino]-3-phenylpropanoate
• CAS NO: 1010128-92-3
• Molecular Weight: 393.422
• Mol File: 1010128-92-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 3-[(diphenylphosphoryl)(methyl)amino]-3-phenylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 3-[(diphenylphosphoryl)(methyl)amino]-3-phenylpropanoate(1010128-92-3)
• EPA Substance Registry System: methyl 3-[(diphenylphosphoryl)(methyl)amino]-3-phenylpropanoate(1010128-92-3)

Safety Data

• Hazardous Substances Data: 1010128-92-3(Hazardous Substances Data)

Upstream product

• 62369-76-0 P-diphenyl(N-benzyl-N-methyl)-λ⁵-phosphinamide 
• 96-32-2 bromoacetic acid methyl ester 

Downstream Products

• 76497-43-3 (R,S)-N-methyl-β-phenyl-β-alanine 

Relevant articles and documents

Phosphinamide-directed benzylic lithiation. application to the synthesis of peptide building blocks

N-Benzyldiphenylphosphinamides are deprotonated at the NCα position diastereospecifically upon treatment with f-BuLi in diethyl ether at low temperature. The reaction of the anions with alkyl, acyl, and tin halides, aliphatic and aromatic aldehydes, and Michael acceptors allowed installation of a variety of functional groups into the benzylic arm in excellent yields. Cleavage of the P-N linkage affords 1,2-amino alcohols and α-, β-, and γ-amino acids.