10129-45-0

Basic information

• Product Name: 1-(2-bromoethyl)pyridinium
• Synonyms: pyridinium, 1-(2-bromoethyl)-
• CAS NO: 10129-45-0
• Molecular Formula: Br*C₇H₉BrN
• Molecular Weight: 187.0565
• Mol File: 10129-45-0.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(2-bromoethyl)pyridinium(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2-bromoethyl)pyridinium(10129-45-0)
• EPA Substance Registry System: 1-(2-bromoethyl)pyridinium(10129-45-0)

Safety Data

• Hazardous Substances Data: 10129-45-0(Hazardous Substances Data)

Usage

Description

1-(2-bromoethyl)pyridinium, with the molecular formula C7H9BrN, is a pyridinium salt featuring a bromoethyl group attached to the pyridine ring. This chemical compound is known for its antimicrobial properties and is utilized in various applications across different industries.

Uses

Used in Organic Synthesis:
1-(2-bromoethyl)pyridinium is used as a reactant in organic synthesis for the creation of various organic compounds, including pharmaceuticals and agrochemicals. Its unique structure allows for versatile chemical reactions, making it a valuable component in the synthesis process.
Used in Antimicrobial Applications:
1-(2-bromoethyl)pyridinium is used as an antimicrobial agent due to its ability to inhibit the growth of certain microorganisms. This property makes it a potential candidate for use in the development of new antimicrobial products and treatments.
Used in Medical Imaging:
1-(2-bromoethyl)pyridinium has been studied for its potential application in medical imaging, where it could be used to enhance the visualization of specific biological processes or structures within the body.
Used in Pharmaceutical Development:
As a potential therapeutic agent, 1-(2-bromoethyl)pyridinium is being investigated for its use in the treatment of certain diseases. Its unique chemical properties may offer new avenues for drug development and therapeutic intervention.
Used in Materials Science:
1-(2-bromoethyl)pyridinium's properties also make it a candidate for use in the development of new materials with specific characteristics, such as those with antimicrobial or other specialized functionalities.

Upstream product

• 110-86-1 pyridine 
• 106-93-4 ethylene dibromide 

Downstream Products

• 76892-40-5 1-(5-methoxy-3-indolylethyl)pyridinium bromide 
• 87012-91-7 1-<2-(phenylthio)ethyl>pyridinium perchlorate 

Relevant articles and documents

Kinetics and mechanism of the formation of N-vinyl pyridinium cations in elimination reactions in aqueous base

The rates of the elimination reactions of N-(2-bromoethyl) pyridinium cations (1) and N,N'-ethylene bispyridinium dications (3) to give the corresponding N-vinyl pyridinium cations (2) have been measured spectrophotometrically in basic aqueous solutions (ionic strength 0.1, 25 deg C) for a variety of substituents in the pyridine rings of each of these classes of pyridinium cation.The reaction kinetics are first order in 1 or 3 and first order in hydroxide ion.Bronsted-type plots of the second-order rate constants (kOH) as a function of the basicity (as pKBH) of the corresponding substituted pyridine are nonlinear for each of 1 and 3 and can be interpreted in terms of E1cb reaction mechanism.For 1, the Bronsted-type plot displays two distinct ''concave down'' linear regions; rate-determining deprotonation for pKBH > 5.16 (slope = -0.30), and a change in rate-determining step to bromide ion departure for pKBH > 5.16 (slope -0.58).For 3, the Bronsted-type plot appears to be smoothly curved for symmetrically disubstituted bispyridinium dications, as a consequence of the multiple substituent effects upon each step of the E1cb reactions of these dications.However, log kOH for 3 is a smooth linear function of the previously reported log kOH for the E1cb reactions of N-(2-cyanoethyl) pyridinium cations over a range in which a change in rate-determining step has been directly demonstrated for these latter cations.Thus a change in rate-determining step as a function of pyridine basicity is also required within the E1cb mechanism for 3.The E1cb reactions of 1 are approximately 104-fold faster than the corresponding hydroxide ion catalyzed E2 eliminations from 2-phenylethyl bromides that are isoelectronic with 1.

Reaction Mechanism of Cathodic Crossed Coupling of Acetone with Unsaturated Compounds in Acidic Solution

It was confirmed that the cathodic crossed coupling of acetone with unsaturated compounds in aqueous sulfuric acid could proceed smoothly, when the compounds which had radical-acceptable double bonds and were adsorbed on a mercury cathode were used.From this fact, it was concluded that the coupling occurs via the addition of a radical intermediate formed by the one-electron reduction of acetone to the double bonds on the cathode surface.Possibility of the addition of an anionic intermediate derived from acetone was excluded by no occurrence of the coupling of acetone with a polar acetylenic triple bond compound adsorbed on the cathode.