1014607-96-5

Basic information

• Product Name: C₃₂H₃₄N₄O₈
• CAS NO: 1014607-96-5
• Molecular Weight: 602.644
• Mol File: 1014607-96-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₂H₃₄N₄O₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₂H₃₄N₄O₈(1014607-96-5)
• EPA Substance Registry System: C₃₂H₃₄N₄O₈(1014607-96-5)

Safety Data

• Hazardous Substances Data: 1014607-96-5(Hazardous Substances Data)

Upstream product

• 147-85-3 L-proline 
• 1014607-94-3 C₂₀H₂₈N₂O₆ 
• 53267-93-9 O-methyl-N-tert-butoxycarbonyl-L-tyrosine 
• 1014607-95-4 C₁₅H₂₀N₂O₄ 
• 152120-55-3 N,N-bis(benzyloxycarbonyl)-1H-pyrazole-1-carboxamidine 

Downstream Products

• 1014607-97-6 C₅₂H₅₃ClN₈O₉ 
• 51871-47-7 H-Tyr-Pro-OH 
• 189388-22-5 endomorphin 1 

Relevant articles and documents

Endomorphin-1 analogs with enhanced metabolic stability and systemic analgesic activity: Design, synthesis, and pharmacological characterization

We synthesized four new analogs of endomorphin-1 by systematic chemical modifications. To identify the best possible drug candidates for clinical pain management and to investigate the potential contribution of these alterations to the biological activity, their pharmacological properties were determined. All of the analogs showed significantly enhanced metabolic stability. The fact that centrally mediated analgesia following peripheral administration was observed with one of the analogs suggested the approach design undertaken here had validity in the development of endomorphin-1 as a successful opioid drug for the clinic.