1016495-38-7Relevant articles and documents
Adenine derivatives invert high glucose-induced thioredoxin-interacting protein overexpression
Zhong, Li,Liu, Qing,Ting, Yan Sie,Thien, Vun Yien,Binti Kalong, Nurwafa Syafiqah,Yang, Dehua,Wang, Ming-Wei
, p. 1998 - 2008 (2018)
Overexpression of thioredoxin-interacting protein (TXNIP) is associated with reduced insulin sensitivity and β-cell apoptosis. We have previously shown that W2476 inhibited high glucose-induced TXNIP expression at both mRNA and protein levels in INS-1E ce