1019582-87-6Relevant articles and documents
4-(5-(cyclohexyloxy) pyridine-2-yl) morpholine-2, 6-diketone and preparation method and application thereof
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Paragraph 0031-0032; 0036-0038, (2021/04/21)
The invention belongs to the field of medicines, and relates to 4-(5-(cyclohexyloxy) pyridine-2-yl) morpholine-2, 6-diketone and a preparation method and application thereof. The structural formula of the 4-(5-(cyclohexyloxy) pyridine-2-yl) morpholine-2, 6-diketone is shown as a formula I. Pharmacological research shows that the compound prepared by the invention can be used as an adrenocorticotropic hormone releasing factor (CRF) receptor antagonist and can be used for treating central nervous system disorders and stress-related disorders caused by CRF endogenous level increase.