1019843-09-4

Basic information

• Product Name: diosgenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->2)-4,6-O-benzylidene-3-O-pivaloyl-β-D-glucopyranoside
• Synonyms: diosgenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->2)-4,6-O-benzylidene-3-O-pivaloyl-β-D-glucopyranoside
• CAS NO: 1019843-09-4
• Molecular Weight: 1079.29
• Mol File: 1019843-09-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: diosgenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->2)-4,6-O-benzylidene-3-O-pivaloyl-β-D-glucopyranoside(CAS DataBase Reference)
• NIST Chemistry Reference: diosgenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->2)-4,6-O-benzylidene-3-O-pivaloyl-β-D-glucopyranoside(1019843-09-4)
• EPA Substance Registry System: diosgenyl 2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl-(1->2)-4,6-O-benzylidene-3-O-pivaloyl-β-D-glucopyranoside(1019843-09-4)

Safety Data

• Hazardous Substances Data: 1019843-09-4(Hazardous Substances Data)

Upstream product

• 74808-10-9 O-(2,3,4,6-Tetra-O-acetyl-α-D-glucopyranosyl)trichloroacetimidate 
• 213753-21-0 diosgenyl 4,6-O-benzylidene-3-O-pivaloyl-β-D-glucopyranoside 

Downstream Products

• 94805-85-3 diosgenyl β-D-glucopyranosyl-(1->2)-β-D-glucopyranoside 

Relevant articles and documents

Synthesis of novel spirostanic saponins and their cytotoxic activity

This study was carried out to assess the cytotoxicity of several new synthetic steroidal saponins against the human myeloid leukemia cell lines (HL-60 and U937) and against human melanoma cells (SK-MEL-1). Several diosgenyl glycosides analyzed showed strong cell growth inhibition which was associated with alterations in cell cycle progression and induction of apoptosis. Studies of cytochrome c release and caspase-9 activation suggest a main role of the intrinsic pathway of apoptosis in the mechanism of cytotoxicity caused by this kind of compounds.