102-03-4

Basic information

• Product Name: N-ACETYL-N'-PHENYLUREA
• Synonyms: 1-acetyl-3-phenyl-ure;n-((phenylamino)carbonyl)-acetamid;phenylureidoaceticacid;N-PHENYL-N'-ACETYLUREA;N-ACETYL-N'-PHENYLUREA;SYM-ACETYLPHENYL UREA;1-acetyl-3-phenylurea;N-[(Phenylamino)carbonyl]acetamide
• CAS NO: 102-03-4
• Molecular Formula: C₉H₁₀N₂O₂
• Molecular Weight: 178.19
• EINECS: 202-999-0
• Mol File: 102-03-4.mol
• Article Data: 7

Chemical Properties

• Melting Point: 183 °C
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.229g/cm³
• Refractive Index: 1.587
• PKA: 12.45±0.70(Predicted)
• CAS DataBase Reference: N-ACETYL-N'-PHENYLUREA(CAS DataBase Reference)
• NIST Chemistry Reference: N-ACETYL-N'-PHENYLUREA(102-03-4)
• EPA Substance Registry System: N-ACETYL-N'-PHENYLUREA(102-03-4)

Safety Data

• Hazardous Substances Data: 102-03-4(Hazardous Substances Data)

Usage

Description

N-Acetyl-N'-phenylurea, also known as N-(phenylcarbamoyl)acetamide, is an organic compound that belongs to the class of urea derivatives. It is characterized by the presence of an amide functional group and a phenyl ring, which contribute to its chemical properties and potential applications.

Uses

Used in Chemical Synthesis:
N-Acetyl-N'-phenylurea is used as an intermediate in the preparation of various urea compounds through the condensation of carbamates with amines. This process allows for the synthesis of a wide range of urea-based compounds with diverse applications in different industries.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-Acetyl-N'-phenylurea can be used as a building block for the development of new drugs with potential therapeutic applications. Its unique structure and reactivity make it a valuable component in the design and synthesis of novel pharmaceutical agents.
Used in Agrochemical Industry:
N-Acetyl-N'-phenylurea can also be utilized in the agrochemical industry for the development of new pesticides and herbicides. Its ability to form urea derivatives with various functional groups makes it a promising candidate for the creation of effective and targeted agrochemical products.

InChI:InChI=1/C9H10N2O2/c1-7(12)10-9(13)11-8-5-3-2-4-6-8/h2-6H,1H3,(H2,10,11,12,13)

Upstream product

• 5378-52-9 phenyl-1H-tetrazole 
• 108-24-7 acetic anhydride 
• 15018-50-5 1-phenyl-pyrimidine-2,4,6-trione 
• 64-10-8 phenyl carbamate 
• 20277-92-3 diphenylguanidine 
• 622-34-4 1-phenylcyanamide 
• 55-21-0 benzamide 
• 89088-94-8 N-Bromacetamid-Natrium 
• 60-35-5 acetamide 
• 103-71-9 phenyl isocyanate 
• 598-49-2 N-chloroacetamide 
• 591-07-1 acetylurea 
• 75-36-5 acetyl chloride 
• 2597-54-8 ethyl acetylcarbamate 

Downstream Products

• 67080-67-5 N-acetylcarbamoyl-sulfanilyl chloride 
• 32767-01-4 N-acetyl-N'-(4-bromo-phenyl)-urea 
• 603-54-3 N,N-diphenylurea 
• 5657-41-0 N³-(4-sulfamoylphenyl)urea 
• 67080-96-0 N-acetyl-N'-(4-sulfamoyl-phenyl)-urea 

Relevant articles and documents

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Synthesis of N-benzothiazol-2-yl-amides by an iron-catalyzed oxidative C(sp2)-H functionalization

Catalytic synthesis of N-benzothiazol-2-yl-amides from 1-acyl-3-(phenyl) thioureas was achieved in the presence of an iron catalyst through C(sp 2)-H functionalization and C-S bond formation. Various N-benzothiazol-2-yl-amides were selectively obtained in good yields. Georg Thieme Verlag Stuttgart, New York.

PYRIDO [2, 3-D] PYRIMIDINES AS WNT ANTAGONISTS FOR TREATMENT OF CANCER AND ARTHRITIS

Compounds according to the general formula (I) their solvates, hydrates, esters and pharmaceutically acceptable salts, their use for modulating the Wnt signalling pathway activity and their use as a medicament, preferably for the treatment of cancer