102017-12-9

Basic information

• Product Name: 3,4-dimethoxy-benzoic acid veratrylidenehydrazide
• Synonyms: 3,4-dimethoxy-benzoic acid veratrylidenehydrazide
• CAS NO: 102017-12-9
• Molecular Weight: 344.367
• Mol File: 102017-12-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 3,4-dimethoxy-benzoic acid veratrylidenehydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-dimethoxy-benzoic acid veratrylidenehydrazide(102017-12-9)
• EPA Substance Registry System: 3,4-dimethoxy-benzoic acid veratrylidenehydrazide(102017-12-9)

Safety Data

• Hazardous Substances Data: 102017-12-9(Hazardous Substances Data)

Upstream product

• 2150-38-1 methyl 3,4-dimethoxybenzoate 
• 41764-74-3 3,4-dimethoxybenzohydrazide 
• 120-14-9 3,4-dimethoxy-benzaldehyde 

Relevant articles and documents

Electrochemical oxidation of aldehyde-N-arylhydrazones into symmetrical-2,5-disubstituted-1,3,4-oxadiazoles

A convenient, efficient and one-pot synthesis of chemically and pharmaceutically interesting symmetrical-2,5-disubstituted-1,3,4-oxadiazoles is reported. The protocol involves anodic oxidation of aldehyde-N-arylhydrazones in anhyd. MeCN-LiClO4. Constant potential electrolysis carried out in an undivided cell and platinum electrodes leads to the formation of the corresponding oxadiazoles under ambient condition and the mechanism was deduced from voltammetry studies. The reaction proceeded smoothly with high atom economy. Springer Science+Business Media Dordrecht 2013.

Hansch analysis of substituted benzoic acid benzylidene/furan-2-yl-methylene hydrazides as antimicrobial agents

A series of substituted hydrazide derivatives have been synthesized and screened for their in vitro antimicrobial activities against five representative microorganisms. The results of antimicrobial study indicated that the presence of electron withdrawing groups on the benzoic acid moiety improved antimicrobial activity. Further, the presence of heterocyclic ring furan does not improve the antimicrobial activity of substituted hydrazides. To understand the relationship between physicochemical parameters and antimicrobial activity of substituted hydrazide derivatives, QSAR investigation was performed by the development of one-target and multi-target models. The multi-target model was found to be effective in describing the antimicrobial activity of substituted hydrazides in comparison to the one-target models. Further, it indicated the importance of the topological parameter, valence third order molecular connectivity index (3χv) and the electronic parameter, energy of highest occupied molecular orbital (HOMO) in describing the antimicrobial activity of substituted hydrazides.