102294-59-7

Basic information

• Product Name: N-(4-iodophenyl)methanesulfonamide
• Synonyms: N-(4-iodophenyl)methanesulfonamide
• CAS NO: 102294-59-7
• Molecular Formula: C₇H₈INO₂S
• Molecular Weight: 297.11339
• Mol File: 102294-59-7.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N-(4-iodophenyl)methanesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-iodophenyl)methanesulfonamide(102294-59-7)
• EPA Substance Registry System: N-(4-iodophenyl)methanesulfonamide(102294-59-7)

Safety Data

• Hazardous Substances Data: 102294-59-7(Hazardous Substances Data)

Upstream product

• 124-63-0 methanesulfonyl chloride 
• 540-37-4 p-aminoiodobenzene 
• 135050-44-1 3-chloro-4-iodoaniline 
• 143937-73-9 N-(3-chloro-4-iodophenyl)methanesulfonamide 
• 110965-10-1 N-(4-Iodophenyl)-N-methylmethanesulphonamide 
• 143937-72-8 N-(2-chloro-4-iodophenyl)methanesulfonamide 
• 42016-93-3 2-chloro-4-iodoaniline 
• 21226-24-4 4-(benzenesulfonylamino)phenyl iodide 
• 98-09-9 benzenesulfonyl chloride 

Downstream Products

• 1020104-97-5 N-[4-(4-trifluoromethoxy-phenoxy)-phenyl]-methanesulfonamide 
• 1020104-95-3 N-[4-(4-methoxy-phenoxy)-phenyl]-methanesulfonamide 
• 1016987-48-6 methyl (2S)-2-hydroxy-3-[N-(4-iodophenyl),N-methanesulfonylamino]propionate 
• 1206772-62-4 N-(4-{(E)-2-[3-(1-hydroxymethyl-cyclopropyl)-5-(2-oxo-1,2-dihydro-pyridin-3-yl)-phenyl]-vinyl}-phenyl)-methanesulfonamide 
• 1246734-66-6 N-(4-((3-tert-butyl-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-2-methoxyphenyl)ethynyl)phenyl)methanesulfonamide 
• 1206775-11-2 N-[4-[(E)-2-(4,4,6-trimethyl-1,3,2-dioxaborinan-2-yl)vinyl]phenyl]methanesulfonamide 
• 1274931-69-9 N-(4-{(E)-2-[2-tert-butyl-6-(2-oxo-1,2-dihydro-pyridin-3-yl)-pyrimidin-4-yl]-vinyl}-phenyl)-methanesulfonamide 
• 1357306-10-5 N-(4-{3-[3-(2-aminoethyl)-2,4-dioxothiazolidin-5-ylidene]-propyl}-phenyl)methanesulfonamide 
• 1380084-83-2 (2-{5-[3-(4-methanesulfonylamino-phenyl)-propylidene]-2,4-dioxo-thiazolidin-3-yl}-ethyl)-carbamic acid tert-butyl ester 
• 1357306-22-9 C₁₀H₁₃NO₃S 
• 1370229-57-4 dithiocarbonic acid S-{2-[methanesulfonyl(4-iodophenyl)amino]-2-oxo-ethyl} ester O-ethyl ester 
• 1370229-67-6 dithiocarbonic acid S-{1-((tert-butoxycarbonylamino)methyl)-4-[methanesulfonyl(4-iodophenyl)amino]-4-oxo-butyl} ester O-ethyl ester 
• 1370229-84-7 5-(2-amino-5-iodophenyl)piperidin-2-one 
• 1370229-42-7 S-1-(4-iodophenylmethanesulfonylamino)-4-cyanobutan-2-yl O-ethyl carbonodithioate 

Relevant articles and documents

Novel sulfonamidospirobifluorenes as fluorescent sensors for mercury(ii) ion and glutathione

Novel spirobifluorene derivatives containing two and four sulfonamide groups are successfully synthesized from the commercially available bromo-9,9′-spirobifluorene by Sonogashira couplings. These compounds exhibit an excellent selective fluorescence quen

Soft-Hard Acid/Base-Controlled, Oxidative, N-Selective Arylation of Sulfonanilides via a Nitrenium Ion

In iodine(III)-catalyzed, dehydrogenative arylations of sulfonanilides, the functionalization of C-C bonds is preferred over the functionalization of C-N bonds. Herein, an unprecedented N-selective arylation of sulfonanilides using soft-hard acid-base (SHAB) control by a nitrenium ion over a carbenium ion is reported. Treatment of sulfonanilides with iodine(III) led to the formation of nitrenium ions (soft), which preferentially react with biphenyls (soft) over bimesityl (hard) to generate C-N bonds. The iodine(III) was generated in situ by using PhI and mCPBA at room temperature.

Palladium-Catalyzed cascade sp2 c?H bond functionalizations allowing one-Pot access to 4?Aryl-1,2,3,4-tetrahydroquinolines from n?Allyl?N?arylsulfonamides

We have developed a palladium-catalyzed cascade reaction allowing an efficient synthesis of 4-aryl-1,2,3,4-tetrahydroquinolines from N-allyl-N-arylsulfonamides and benzenesulfonyl chlorides. In this transformation, two C(sp2)?C(sp3) bonds were formed via activation of C(sp2)?H bonds. The reaction proceeds using the easily accessible catalyst PdCl2, with Li2CO3 as inexpensive base and CuBr as additive, and tolerates a wide variety of substituents on both reaction partners.