102423-74-5

Basic information

• Product Name: 4H-Thiopyran-3,5-dicarbonitrile, 2,6-diamino-4-(4-methoxyphenyl)-
• CAS NO: 102423-74-5
• Molecular Formula: C14H12N4OS
• Molecular Weight: 284.341
• Mol File: 102423-74-5.mol
• Article Data: 7

Chemical Properties

• CAS DataBase Reference: 4H-Thiopyran-3,5-dicarbonitrile, 2,6-diamino-4-(4-methoxyphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Thiopyran-3,5-dicarbonitrile, 2,6-diamino-4-(4-methoxyphenyl)-(102423-74-5)
• EPA Substance Registry System: 4H-Thiopyran-3,5-dicarbonitrile, 2,6-diamino-4-(4-methoxyphenyl)-(102423-74-5)

Safety Data

• Hazardous Substances Data: 102423-74-5(Hazardous Substances Data)

Usage

Chemical compound

4H-Thiopyran-3,5-dicarbonitrile, 2,6-diamino-4-(4-methoxyphenyl)-

Class

Thiopyrans

Description

Heterocyclic compound containing a five-membered sulfur ring fused to a six-membered pyran ring

Functional groups present

Two cyano groups, two amino groups, and a methoxyphenyl group

Applications

Used in organic synthesis and medicinal chemistry as a building block for the synthesis of biologically active compounds

Potential applications

Development of pharmaceuticals and agrochemicals due to diverse reactivity and structural features

Upstream product

• 7357-70-2 Cyanothioacetamide 
• 123-11-5 4-methoxy-benzaldehyde 
• 109-77-3 malononitrile 
• 107-10-8 propylamine 
• 75-15-0 carbon disulfide 
• 106763-17-1 4-methoxybenzylidenecyanothioacetamide 
• 39145-31-8 2-cyano-3-(4-methoxyphenyl)thioacrylamide 
• 2826-26-8 2-(4-methoxyphenylmethylene)malononitrile 

Downstream Products

• 110691-01-5 6-amino-4-(4-methoxyphenyl)-2-thioxo-1,2-dihydropyridine-3,5-dicarbonitrile 
• 299464-98-5 3,6-diamino-5-cyano-4-(4-methoxyphenyl)-thieno[2,3-b]pyridine-2-carboxamide 
• 110691-01-5 2-amino-4-(4-methoxyphenyl)-6-mercaptopyridine-3,5-dicarbonitrile 
• 14482-11-2 p-methoxycinnamonitrile 

Relevant articles and documents

Multicomponent Synthesis of 4-Alkyl(Aryl, Hetaryl)-2-alkoxycarbonyl(aroyl, carbamoyl)- 3,6-diamino-5-cyanothieno[2,3-b]pyridines

The condensation of malononitrile with hydrogen sulfide and aldehydes in the presence of triethylamine in ethanol at room temperature afforded 4-alkyl(aryl, hetaryl)-2,6-diamino-3,5-dicyano-4H-thiopyrans. Treatment of the latter in situ with alkali in DMF, followed by addition of an alkylating agent, led to the formation of 4-alkyl(aryl, hetaryl)-2-alkoxycarbonyl(aroyl, carbamoyl)-3,6-diamino-5-cyanothieno[2,3-b]- pyridines.

ACETYL-COA CARBOXYLASE MODULATORS

Provided herein are compounds that exhibit activity as acetyl-CoA carboxylase modulators (e.g., inhibitors) and are useful, for example, in methods for the control of fungal pathogens in plants.

Activated Nitriles in Heterocyclic Synthesis: The Reaction of Cyanothioacetamide with Activated Double Bond Systems

Die Reaktion von Benzylidenmalononitrilen mit Cyanthioacetamid (1) ergibt je nach den Reaktionsbedingungen entweder Thiopyrane oder Pyridine.Die Strukturen der Reaktionsprodukte wurden mittels 13C-NMR aufgeklaert.