102507-13-1 Usage
Description
N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID, also known as N-Boc-3-hydroxy-L-valine, is a white powder chemical compound with significant applications in the pharmaceutical industry. It is a derivative of L-valine, an essential amino acid, with a hydroxyl group and a BOC-protecting group attached to it. N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID is known for its role in the synthesis of various metabolites and pharmaceutical compounds.
Uses
Used in Pharmaceutical Synthesis:
N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID is used as a reagent for the synthesis of metabolites of PPI-2458, a selective, irreversible inhibitor of methionine aminopeptidase-2 (MetAP2). This application is significant in the development of potential therapeutic agents for various diseases.
Used in Hepatitis C Treatment:
N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID is also used in the preparation of Boceprevir (B674500), an NS3 serine protease inhibitor of the hepatitis C virus. Boceprevir is an essential component in the treatment of HCV infection, helping to combat the virus and alleviate the symptoms associated with the disease.
Used in Research and Development:
In the field of research and development, N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID serves as a valuable compound for the synthesis of various pharmaceutical compounds and the study of their properties and potential applications in medicine.
Used in the Chemical Industry:
N-BOC-(S)-2-AMINO-3-HYDROXY-3-METHYLBUTANOIC ACID is utilized in the chemical industry for the synthesis of various intermediates and specialty chemicals, contributing to the development of new products and technologies.
Check Digit Verification of cas no
The CAS Registry Mumber 102507-13-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,5,0 and 7 respectively; the second part has 2 digits, 1 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 102507-13:
(8*1)+(7*0)+(6*2)+(5*5)+(4*0)+(3*7)+(2*1)+(1*3)=71
71 % 10 = 1
So 102507-13-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H19NO5/c1-9(2,3)16-8(14)11-6(7(12)13)10(4,5)15/h6,15H,1-5H3,(H,11,14)(H,12,13)/t6-/m1/s1
102507-13-1Relevant articles and documents
Total synthesis of nannocystin Ax
Zhang, Yan-Hui,Liu, Rong,Liu, Bo
, p. 5549 - 5552 (2017)
A concise total synthesis of nannocystin Ax, a natural depsipeptide recently isolated from myxobacteria, has been accomplished. By following a convergent strategy, the target molecule was assembled from three fragments. Each fragment can be synthesized expeditiously from readily achievable compounds. The key elements in this total synthesis feature Kobayashi's remote asymmetric induction with vinylketene silyl N,O-acetal, Roush's asymmetric crotylboration of aldehyde, Mitsunobu's esterification and macrocyclization via Stille cross-coupling.
Gold-Catalyzed Amide/Carbamate-Linked N, O-Acetal Formation with Bulky Amides and Alcohols
Ohsawa, Kosuke,Ochiai, Shota,Kubota, Junya,Doi, Takayuki
, p. 1281 - 1291 (2021)
A gold-catalyzed N,O-acetal formation was established to construct an amide/carbamate-linked N,O-acetal substructure with bulky alcohols. The acyliminium cation species generated from o-alkynylbenzoic acid ester in the presence of a gold catalyst is highly reactive and underwent nucleophilic attack of various bulky alcohols and phenols at room temperature under neutral conditions, leading to the corresponding N,O-acetals in yields of 34-89% with good functional group tolerance.
MONOBACTAM COMPOUNDS AND USE THEREFOR
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, (2022/01/12)
Monobactam compounds and a use therefor. Specifically provided are chemical compounds represented by formula (I) or isomers, pharmaceutically acceptable salts, solvates, crystals, or prodrugs thereof, preparation methods therefor, pharmaceutical compositions containing said compounds, and a use of said compounds or compositions in treating bacterial infection. The present compounds feature excellent antibacterial activity, and have great hopes of becoming a therapeutic agent for bacterial infection.
APPLICATION OF MONOCYCLIC BETA-LACTAM COMPOUND IN PHARMACY
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, (2021/11/04)
An application of a compound represented by formula (I) and pharmaceutically acceptable salts thereof in preparation of a drug for treating pneumonia.