102539-79-7

Basic information

• Product Name: 6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID
• Synonyms: 6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID;Benzo[b]thiophene-2-carboxylic acid, 6-Methoxy-;6-Methoxy-1-benzothiophene-2-carboxylic acid;6-methoxy-2-benzothiophenecarboxylic acid
• CAS NO: 102539-79-7
• Molecular Formula: C₁₀H₈O₃S
• Molecular Weight: 208.23
• Mol File: 102539-79-7.mol
• Article Data: 6

Chemical Properties

• Melting Point: 248.5-249 °C(Solv: acetone (67-64-1); benzene (71-43-2))
• Boiling Point: 410 °C at 760 mmHg
• Flash Point: 201.8 °C
• Appearance: /
• Density: 1.392 g/cm³
• Vapor Pressure: 1.86E-07mmHg at 25°C
• Refractive Index: 1.673
• Storage Temp.: 2-8°C
• PKA: 3.58±0.30(Predicted)
• CAS DataBase Reference: 6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID(102539-79-7)
• EPA Substance Registry System: 6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID(102539-79-7)

Safety Data

• Hazardous Substances Data: 102539-79-7(Hazardous Substances Data)

Usage

General Description

6-Methoxy-benzo[b]thiophene-2-carboxylic acid is a chemical compound with the molecular formula C11H8O3S. It is a benzo[b]thiophene derivative with a carboxylic acid functional group and a methoxy substituent. 6-METHOXY-BENZO[B]THIOPHENE-2-CARBOXYLIC ACID is commonly used in the synthesis of pharmaceuticals and agrochemicals due to its potential biological activity. It is also used in the production of dyes and pigments. 6-Methoxy-benzo[b]thiophene-2-carboxylic acid may have applications in the development of new drugs or as a building block in organic synthesis. Overall, its unique chemical structure and potential biological activity make it a valuable compound in various industries.

InChI:InChI=1/C10H8O3S/c1-13-7-3-2-6-4-9(10(11)12)14-8(6)5-7/h2-5H,1H3,(H,11,12)

Upstream product

• 90560-10-4 6-methoxy-benzo[b]thiophene 
• 22546-89-0 6-methoxy-benzothiophene-3-ol 
• 3996-32-5 [(3-methoxyphenyl)sulfanyl]acetic acid 
• 550998-58-8 6-methoxybenzo[b]thiophene-2-carboxylic acid methyl ester 
• 331-64-6 2-fluoro-4-methoxy-benzaldehyde 
• 22996-21-0 4-methoxy-2-nitro-benzaldehyde 
• 187753-62-4 ethyl 6-methoxybenzo[b]thiophene-2-carboxylate 

Downstream Products

• 1929-29-9 3-(4-methoxyphenyl)propanoic acid 
• 101875-55-2 6-methoxy-benzo[b]thiophene-2-carboxylic acid-(4-bromo-phenacyl ester) 
• 1104630-91-2 N-(3,4-difluoro-benzyl)-N-(6-methoxy-benzo[b]thiophen-2-yl)-pyridin-3-yl-sulfonamide 
• 1104623-18-8 N-(3-bromo-6-methoxy-benzo[b]thiophen-2-yl)-N-(3,4-difluoro-benzyl)-pyridin-3-yl-sulfonamide 
• 1432040-88-4 6-hydroxybenzo[b]thiophene-2-carboxylic acid 
• 90560-10-4 6-methoxy-benzo[b]thiophene 
• 19301-39-4 1-benzothiophen-6-ol 

Relevant articles and documents

Substituted benzothiophene and benzofuran derivatives as a novel class of bone morphogenetic Protein-2 upregulators: Synthesis, anti-osteoporosis efficacies in ovariectomized rats and a zebrafish model, and ADME properties

The bone morphogenetic protein (BMP) pathway is a promising new target for the design of therapeutic agents for the treatment of low bone mass. This study optimized the structure of the anti-osteoporosis compound 38 by balancing its lipophilicity and impr

CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE

Described herein are compounds, methods of making such compounds, pharmaceutical compositions and medicaments containing such compounds, and methods of using such compounds to treat or prevent diseases or disorders associated with the enzyme ceramide galactosyltransferase (CGT), such as, for example, lysosomal storage diseases. Examples of lysosomal storage diseases include, for example, Krabbe disease and Metachromatic Leukodystrophy.

SULFONAMIDES AS TRPM8 MODULATORS

Disclosed are compounds, compositions and methods for treating various diseases, syndromes, conditions and disorders, including pain. Such compounds are represented by Formula I as follows: wherein A, B, G, Y, R1, R2, R3, and R4 are defined herein.