1026945-35-6

Basic information

• Product Name: 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-diphenyl-propionic acid methyl ester
• Synonyms: 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-diphenyl-propionic acid methyl ester
• CAS NO: 1026945-35-6
• Molecular Weight: 438.48
• Mol File: 1026945-35-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-diphenyl-propionic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-diphenyl-propionic acid methyl ester(1026945-35-6)
• EPA Substance Registry System: 2-(4,6-Dimethoxy-pyrimidin-2-yloxy)-3-ethoxy-3,3-diphenyl-propionic acid methyl ester(1026945-35-6)

Safety Data

• Hazardous Substances Data: 1026945-35-6(Hazardous Substances Data)

Upstream product

• 76527-25-8 3,3-diphenyloxirane-2-carboxylic acid methyl ester 
• 119-61-9 benzophenone 
• 113583-35-0 4,6-dimethoxypyrimidin-2-yl methyl sulfone 
• 443668-42-6 3-Ethoxy-2-hydroxy-3,3-diphenyl-propionic acid methyl ester 

Relevant articles and documents

Discovery and optimization of a novel class of orally active nonpeptidic endothelin-A receptor antagonists

A novel class of endothelin-A receptor ligands was discovered by high-throughput screening. Lead structure optimization led to highly potent antagonists which can be synthesized in a short sequence. The compounds are endothelin-A-selective, are orally available, and show a long duration of action.