1027137-63-8Relevant articles and documents
Synthesis of β-secretase inhibitors containing a hydroxyethylene dipeptide isostere
Yang, Xiaoming,Zou, Xiaomin,Fu, Yiqiu,Mou, Ke,Fu, Gang,Ma, Chao,Xu, Ping
, p. 9 - 24 (2007)
β-Secretase inhibitors with a Leu* Ala hydroxyethylene dipeptide (HED) isostere have been an especially interesting topic in recent years. In this study, a template compound 17 was synthesized, featuring truncation at the P2′ position and changes at P2 an