102855-24-3

Basic information

• Product Name: 4-chloro-1-tosyl-1H-indole
• Synonyms: 4-chloro-1-tosyl-1H-indole;1H-Indole, 4-chloro-1-[(4-methylphenyl)sulfonyl]-;4-Chloro-1-Tosyl-1H-Indole(WXC02466)
• CAS NO: 102855-24-3
• Molecular Formula: C₁₅H₁₂ClNO₂S
• Molecular Weight: 305.77928
• Mol File: 102855-24-3.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 4-chloro-1-tosyl-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-1-tosyl-1H-indole(102855-24-3)
• EPA Substance Registry System: 4-chloro-1-tosyl-1H-indole(102855-24-3)

Safety Data

• Hazardous Substances Data: 102855-24-3(Hazardous Substances Data)

Usage

Uses

4-Chloro-1-tosyl-1H-indole is a useful reagent in organic synthesis.

Upstream product

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Relevant articles and documents

Silver-Catalyzed Asymmetric Dearomatization of Electron-Deficient Heteroarenes via Interrupted Barton–Zard Reaction

Herein we report a catalytic asymmetric dearomatization reaction of electron-deficient heteroarenes with α-substituted isocyanoacetates through an interrupted Barton–Zard reaction. A range of optically active pyrrolo[3,4-b]indole derivatives was obtained

Practical and Scalable Synthesis of Borylated Heterocycles Using Bench-Stable Precursors of Metal-Free Lewis Pair Catalysts

A practical and scalable metal-free catalytic method for the borylation and borylative dearomatization of heteroarenes has been developed. This synthetic method uses inexpensive and conveniently synthesizable bench-stable precatalysts of the form 1-NHR2-2-BF3-C6H4, commercially and synthetically accessible heteroarenes as substrates, and pinacolborane as the borylation reagent. The preparation of several borylated heterocycles on 2 and 50 g scales was achieved under solvent-free conditions without the use of Schlenk techniques or a glovebox. A kilogram-scale borylation of one of the heteroarene substrates was also achieved using this cost-effective green methodology to exemplify the fact that our methodology can be conveniently implemented in fine chemical industries.

A Synthetic Route to 2-Alkyl Indoles via Thiophenol-Mediated Ring-Opening of N-Tosylaziridines Followed by Copper Powder-Mediated C-N Cyclization/Aromatization

A simple strategy for the syntheses of 2-alkyl indoles via regioselective ring-opening of 2-(2-haloaryl)-3-alkyl-N-tosylaziridines with thiophenol, followed by copper powder-mediated intramolecular C-N cyclization and subsequent aromatization by the elimi