102978-40-5 Usage
Description
(±)1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy is a heterocyclic compound characterized by a pyranoindolizine core structure. It features a trione functional group and a hydroxyl group, with an ethyl substituent at the 4-position of the core structure. (±)1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy possesses potential biological activity and may be utilized in medicinal or pharmaceutical applications. Its 7,8-dihydro-4-hydroxy group implies the presence of antioxidant properties, and its heterocyclic structure suggests possible interactions with biological receptors or enzymes. Further research and testing are required to determine its specific uses and effects.
Uses
Used in Pharmaceutical Applications:
(±)1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy is used as a potential pharmaceutical agent for its possible biological activity. Its heterocyclic structure allows for interactions with biological receptors or enzymes, which may contribute to its medicinal properties.
Used in Antioxidant Formulations:
In the health and wellness industry, (±)1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy is used as an antioxidant due to its 7,8-dihydro-4-hydroxy group. This feature may provide protective effects against oxidative stress and support overall health.
Used in Drug Development Research:
(±)1H-Pyrano[3,4-f]indolizine-3,6,10(4H)-trione, 4-ethyl-7,8-dihydro-4-hydroxy is utilized in drug development research to explore its potential as a lead compound for the creation of new medications. Its unique structure and properties make it a candidate for further investigation into its therapeutic potential.
Check Digit Verification of cas no
The CAS Registry Mumber 102978-40-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,2,9,7 and 8 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 102978-40:
(8*1)+(7*0)+(6*2)+(5*9)+(4*7)+(3*8)+(2*4)+(1*0)=125
125 % 10 = 5
So 102978-40-5 is a valid CAS Registry Number.
102978-40-5Relevant articles and documents
Plant antitumor agents. 22. Isolation of 11-hydroxycamptothecin from Camptotheca acuminata Decne: Total synthesis and biological activity
Wall,Wani,Natschke,Nicholas
, p. 1553 - 1555 (1986)
-
Preparation method of three-membered ring compound
-
Paragraph 0022; 0040-0041, (2021/02/10)
The invention discloses a preparation method of a three-membered ring compound. The compound is an important intermediate for preparing racemic camptothecin compounds. The method comprises the following steps of: taking 6-chlorine-2-methoxy nicotinic acid as an initial raw material, and reacting the 6-chlorine-2-methoxy nicotinic acid with 1-pentene-3-ketone and a lithium reagent to obtain a lactone compound; reducing lactone to obtain a diol compound; oxidizing the diol compound to obtain a hemiacetal compound; oxidizing the hemiacetal compound to obtain a lactone compound; inserting carbonylinto the lactone compound to obtain a 6-position n-propyl ester compound; demethylating the n-propyl ester compound to form a pyridone compound; and finally, reacting the pyridone compound with tert-butyl acrylate, and decarboxylating to obtain the three-membered ring compound, namely 4-ethyl-4-hydroxyl-7, 8-dihydro-1H-pyrano [3, 4-f] indolizine-3, 6, 10 (4H)-triketone. The method is high in yield, short in synthesis route, simple and cheap in raw materials and easy in purification.
Hexa-cyclic camptothecin derivatives
-
, (2008/06/13)
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: STR1 The compound is prepared from an aminoketone compound and a pyranoindolizine compound through Friedlaender reaction. It has an excellent antitumor activity and a high