1033827-24-5

Basic information

• Product Name: ethyl {4-([(2,4-dinitrophenyl)hydrazono]-(4-ethoxycarbonyl-methoxyphenyl)-methyl)-phenoxy}-ethanoate
• Synonyms: ethyl {4-([(2,4-dinitrophenyl)hydrazono]-(4-ethoxycarbonyl-methoxyphenyl)-methyl)-phenoxy}-ethanoate
• CAS NO: 1033827-24-5
• Molecular Weight: 566.524
• Mol File: 1033827-24-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl {4-([(2,4-dinitrophenyl)hydrazono]-(4-ethoxycarbonyl-methoxyphenyl)-methyl)-phenoxy}-ethanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl {4-([(2,4-dinitrophenyl)hydrazono]-(4-ethoxycarbonyl-methoxyphenyl)-methyl)-phenoxy}-ethanoate(1033827-24-5)
• EPA Substance Registry System: ethyl {4-([(2,4-dinitrophenyl)hydrazono]-(4-ethoxycarbonyl-methoxyphenyl)-methyl)-phenoxy}-ethanoate(1033827-24-5)

Safety Data

• Hazardous Substances Data: 1033827-24-5(Hazardous Substances Data)

Upstream product

• 2675-35-6 4,4'-dihydroxybenzophenone-2,4-dinitrophenylhydrazone 
• 105-36-2 ethyl bromoacetate 

Downstream Products

• 1033827-19-8 (4-{(4-carboxymethoxy-phenyl)-[(2,4-dinitro-phenyl)-hydrazono]-methyl}-phenoxy)-acetic acid 

Relevant articles and documents

NMR spectroscopic study of cyclodextrin inclusion complexes with A-007 prodrugs

One- and two-dimensional NMR spectroscopy was used to demonstrate the formation of inclusion cyclodextrin complexes with several A-007 prodrugs. These complexes are comprised from the encapsulation of the two phenol moieties of the A-007 prodrugs within the cyclodextrin cavity. Considering the size of the two phenol moieties of the A-007 prodrugs compared to the sizes of α-, β-, and γ-cyclodextrin cavities, we observed complementary binding of the A-007 prodrug with only β-cyclodextrin, which was also demonstrated spectroscopically. The β-cyclodextrin inclusion complexes increased the prodrug solubility and modified the prodrug half-life in water. Therefore, β-cyclodextrin inclusion complexes can be used as an essential form of A-007 prodrug delivery.