103404-75-7

Basic information

• Product Name: D-LUCIFERIN SODIUM SALT
• Synonyms: (S)-2-(6-HYDROXY-2-BENZOTHIAZOLYL)-2-THIAZOLINE-4-CARBOXYLIC ACID SODIUM SALT;FIREFLY LUCIFERIN MONOSODIUM SALT MONOHYDRATE;FIREFLY LUCIFERIN SODIUM SALT;D-LUCIFERIN, MONOSODIUM SALT;D-LUCIFERIN SODIUM SALT;D(-)-LUCIFERIN SODIUM SALT MONOHYDRATE;D-LUCIFERIN SODIUM SALT MONOHYDRATE;D-(-)-2-[6'-HYDROXY-2'-BENZOTHIAZOLYL]DELTA-THIAZOLINE-4-CARBOXYLIC ACID SODIUM SALT
• CAS NO: 103404-75-7
• Molecular Formula: C11H7N2NaO3S2
• Molecular Weight: 302.3
• EINECS: 600-430-4
• Mol File: 103404-75-7.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 473.7°C at 760 mmHg
• Flash Point: 240.3°C
• Appearance: Yellow/lyophilized powder
• Vapor Pressure: 2.78E-10mmHg at 25°C
• Storage Temp.: −20°C
• Solubility: H2O: soluble
• CAS DataBase Reference: D-LUCIFERIN SODIUM SALT(CAS DataBase Reference)
• NIST Chemistry Reference: D-LUCIFERIN SODIUM SALT(103404-75-7)
• EPA Substance Registry System: D-LUCIFERIN SODIUM SALT(103404-75-7)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-36/37/39-26
• WGK Germany: 3
• F: 10-21-23
• Hazardous Substances Data: 103404-75-7(Hazardous Substances Data)

Usage

Description

D-Luciferin sodium salt, a chemiluminescent substrate of firefly luciferase, is a small molecule that can easily cross the blood-testis barrier, blood-brain barrier, and blood-placenta barrier. It is sensitive to light, oxygen, and moisture in its powder form. D-Luciferin produces light upon oxidative decarboxylation by luciferase in the presence of ATP, making it a valuable tool in various assays and applications.

Uses

Used in Bioluminescent Assays:
D-Luciferin sodium salt is used as a substrate for firefly luciferase in bioluminescent assays, allowing the assessment of ATP levels and luciferase activity.
Used in ATP and Luciferase Assays:
D-Luciferin sodium salt is employed in luciferase assays and determination of ATP, providing a means to measure the presence and concentration of ATP in various samples.
Used in Luciferin-Luciferase Chemiluminescence Assay:
D-Luciferin sodium salt has been utilized as a substrate in the luciferin-luciferase chemiluminescence assay to determine ATP levels, offering a reliable method for quantifying ATP in different biological systems.
Used in Gene Expression Assays:
D-Luciferin can be used to assay the expression of the luciferase gene linked to a promoter of interest, providing insights into gene regulation and activity.
Used in Cellular or Biochemical Assays:
D-Luciferin and luciferase can be used to assess ATP availability in cellular or biochemical assays, offering a valuable tool for studying cellular metabolism and energy production.
Chemical Properties:
D-Luciferin sodium salt is a yellow powder with chemiluminescent properties, making it a versatile compound for various applications in research and diagnostics.

InChI:InChI=1/C11H8N2O3S2/c14-5-1-2-6-8(3-5)18-10(12-6)9-13-7(4-17-9)11(15)16/h1-3,7,13H,4H2,(H,15,16)/p-1/t7-/m1/s1