103452-54-6Relevant articles and documents
OPTICALLY ACTIVE HETEROAROMATIC COMPOUNDS. IX. THE SYNTHESIS OF MONOALKYL-SUBSTITUTED OPTICALLY ACTIVE PYRIDINES
Azzena, Ugo,Chelucci, Giorgio,Delogu, Giovanna,Gladiali, Serafino,Marchetti, Mauro,et al.
, p. 307 - 316 (2007/10/02)
Optically active 2-, 3-, or 4-monoalkyl-substituted pyridines bearing the chirality centre at the alkyl group have been synthesized by several different synthetic procedures starting from easily available chiral synthons.Scopes and limitations of the synthetic methods as well as the relationships between the optical activity and the optical purity of the products are discussed.