10354-29-7

Basic information

• Product Name: 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(1,3-BENZODIOXOL-5-YL)-1,4-DIHYDRO-2,6-DIMETHYL-, DIETHYL ESTER
• Synonyms: 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(1,3-BENZODIOXOL-5-YL)-1,4-DIHYDRO-2,6-DIMETHYL-, DIETHYL ESTER;diethyl 4-(1,3-benzodioxol-5-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• CAS NO: 10354-29-7
• Molecular Formula: C20H23NO6
• Molecular Weight: 373.4
• Mol File: 10354-29-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 492.1°C at 760 mmHg
• Flash Point: 251.4°C
• Appearance: /
• Density: 1.225g/cm³
• Vapor Pressure: 7.9E-10mmHg at 25°C
• Refractive Index: 1.548
• CAS DataBase Reference: 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(1,3-BENZODIOXOL-5-YL)-1,4-DIHYDRO-2,6-DIMETHYL-, DIETHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(1,3-BENZODIOXOL-5-YL)-1,4-DIHYDRO-2,6-DIMETHYL-, DIETHYL ESTER(10354-29-7)
• EPA Substance Registry System: 3,5-PYRIDINEDICARBOXYLIC ACID, 4-(1,3-BENZODIOXOL-5-YL)-1,4-DIHYDRO-2,6-DIMETHYL-, DIETHYL ESTER(10354-29-7)

Safety Data

• Hazardous Substances Data: 10354-29-7(Hazardous Substances Data)

Usage

InChI:InChI=1/C20H23NO6/c1-5-24-19(22)16-11(3)21-12(4)17(20(23)25-6-2)18(16)13-7-8-14-15(9-13)27-10-26-14/h7-9,18,21H,5-6,10H2,1-4H3

Upstream product

• 120-57-0 piperonal 
• 141-97-9 ethyl acetoacetate 
• 626-34-6 ethyl aminocrotonate 
• 7664-41-7 ammonia 
• 631-61-8 ammonium acetate 

Relevant articles and documents

Hantzsch 1,4-dihydropyridine synthesis in aqueous ethanol by visible light

A highly efficient environment-friendly Hantzsch 1,4-dihydropyridine synthesis under visible light in aqueous ethanol has been achieved in excellent yield via a one-pot three component reaction of various types of aliphatic and aromatic aldehydes with ethyl acetoacetate and ammonium hydroxide solution.

2-Hydroxyethylammonium acetate: An efficient and reusable homogeneous catalyst for the synthesis of Hantzsch 1, 4-dihydropyridines

2-Hydroxyethylammonium acetate ionic liquid was found to be an excellent catalyst for the one-pot synthesis of 1,4-dihydropyridine derivatives via Hantzsch reaction of ethyl acetoacetate or acetoacetanilide, ammonium acetate, and various aromatic aldehyde

Silica sulfuric acid: An efficient heterogeneous catalyst for the one-pot synthesis of 1,4-dihydropyridines under mild and solvent-free conditions

A series of 1,4-dihydropyridines have been prepared by a one-pot condensation of aldehydes, ethyl acetoacetate, and ammonium acetate in the presence of a heterogeneous catalyst silica sulfuric acid at room temperature under solvent-free condition. This new protocol has the advantage of short reaction time and excellent yields, and is an environmentally benign route to the synthesis of 1,4-dihydropyridines.