103647-45-6Relevant articles and documents
Efficient synthesis of α-benzylidene-γ-methyl-γ-butyrolactones
Mali, Raghao S.,Babu, Kantipudi N.
, p. 3525 - 3531 (2007/10/03)
A concise synthesis of α-benzylidene-γ-methyl-γ-butyrolactones 5a - g from substituted benzaldehydes is described. Compounds 1a - g on reaction with phosphorane 2, provide the pentenoates 3a - g, which can be hydrolyzed to the acids 4a - g. The latter are cyclized to the corresponding butyrolactones 5a - g in excellent yields. The pentenoates 3a - g, on acid catalyzed cyclization, also provide 5a - g in very high yields.
