103711-21-3 Usage
Description
Acetic acid, diamino-, also known as 2,2-Diaminoacetic Acid, is an organic compound characterized by the presence of two amine groups attached to the same carbon atom. It plays a crucial role in the formation of peptide and conjugation linkers, which are essential for enhancing the interactions between drug analogues and their target enzymes.
Uses
Used in Pharmaceutical Industry:
Acetic acid, diaminois used as a building block for the synthesis of peptide linkers and conjugation linkers for improving the interaction between drug analogues and their enzymes. This application is particularly relevant in the development of novel drugs and drug delivery systems, as it can enhance the efficacy and specificity of therapeutic agents.
Used in Drug Development:
Acetic acid, diaminois used as a key component in the development of new drugs, particularly those targeting specific enzymes. By forming peptide and conjugation linkers, it can help create more effective and targeted drug molecules, leading to improved treatment options for various diseases and conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 103711-21-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,3,7,1 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 103711-21:
(8*1)+(7*0)+(6*3)+(5*7)+(4*1)+(3*1)+(2*2)+(1*1)=73
73 % 10 = 3
So 103711-21-3 is a valid CAS Registry Number.
103711-21-3Relevant articles and documents
The Reaction of Glyoxylic Acid with Ammonia Revisited
Hoefnagel, Anthonius J.,Bekkum, Herman van,Peters, Joop A.
, p. 3916 - 3921 (2007/10/02)
Upon addition of ammonia or an alkylamine to glyoxylic acid an ammonium derivative of glyoxylic acid precipitates quantitatively.With the use of solid-state 13C and 15N NMR spectroscopy, it is shown that adducts of glyoxylic acid and ammonia or the alkylamine are obtained.These compounds are not stable in aqueous solution.The compositions of the aqueous solutions have been investigated by 1H, 13C, 15N, and 17O NMR.Under basic conditions hexahydro-s-triazine-2,4,6-tricarboxylate is the predominant species in a solution of the adduct of ammonia and glyoxylic acid, whereas upon acidification (pH 6) glyoxylate is the only organic species.In a basic solution of the adduct of ethylamine and glyoxylic acid N-ethyliminoacetate is the only species.The N-methyl adduct shows an intermediate behavior: both the hexahydrotriazine and the imine are observed.Under acidic conditions deamination to glyoxylate always occurs.Intermediates in the reaction of glyoxylic acid and ammonia could be detected with 1H NMR, when the reaction was performed with an excess of ammonia.The mechanism of these reactions is discussed.
