103986-76-1

Basic information

• Product Name: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID
• Synonyms: Cinnamicacid, 2-methoxy-5-methyl- (6CI); 2-Methoxy-5-methylcinnamic acid;3-(2-Methoxy-5-[methyl]phenyl)acrylic acid
• CAS NO: 103986-76-1
• Molecular Formula: C₁₁H₁₂O₃
• Molecular Weight: 192.21
• Mol File: 103986-76-1.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 339.6°Cat760mmHg
• Flash Point: 132.8°C
• Appearance: /
• Density: 1.162g/cm³
• Vapor Pressure: 3.53E-05mmHg at 25°C
• CAS DataBase Reference: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID(103986-76-1)
• EPA Substance Registry System: (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID(103986-76-1)

Safety Data

• Hazardous Substances Data: 103986-76-1(Hazardous Substances Data)

Usage

General Description

(2E)-3-(2-methoxy-5-methylphenyl)acrylic acid, also known as o-anisalacrylic acid, is a chemical compound with the molecular formula C11H12O3. It is a derivative of acrylic acid and belongs to the class of aromatic acrylates. (2E)-3-(2-METHOXY-5-METHYLPHENYL)ACRYLIC ACID is commonly used in organic synthesis and pharmaceutical research as a building block for the synthesis of various organic compounds. It is also known for its potential biological activities and is being studied for its potential use in the development of pharmaceutical drugs. Additionally, it has been reported to have antioxidant and anti-inflammatory properties, making it of interest for medicinal and cosmetic applications.

InChI:InChI=1/C11H12O3/c1-8-3-5-10(14-2)9(7-8)4-6-11(12)13/h3-7H,1-2H3,(H,12,13)/p-1/b6-4+

Upstream product

• 107274-42-0 2-methoxy-5-methyl-cinnamic acid ethyl ester 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 7083-19-4 2-methoxy-5-methylbenzaldehyde 
• 92-48-8 6-methylcoumarin 
• 77-78-1 dimethyl sulfate 
• 858786-32-0 3-hydroxy-3-(2-methoxy-5-methyl-phenyl)-propionic acid ethyl ester 
• 108-24-7 acetic anhydride 
• 141-82-2 malonic acid 
• 22002-45-5 2-bromo-4-methylanisole 
• 1194827-68-3 ethyl (E)-3-(2-methoxy-5-methylphenyl)acrylate 

Downstream Products

• 61371-44-6 3-(2'-methoxy-5-methylphenyl)propanoic acid 
• 889135-71-1 (E)-3-(2-methoxy-5-methylphenyl)acrylaldehyde 
• 857288-55-2 (S)-3-(2-methoxy-5-methylphenyl)-3-phenylpropanal 
• 124937-55-9 4-(2-Methoxy-5-methylphenyl)-6-methyl-3,4-dihydrocoumarin 

Relevant articles and documents

TETRAHYDROBENZOTHIOPHENE DERIVATIVES

Compounds of a certain formula I, in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.

NTETRAHYDROPYRIDOTHIOPHENE DERIVATIVES FOR THE TREATMENT OF CANCER

Compounds of a certain formula (I), in which Ra and Rb have the meanings indicated in the description, are novel effective compounds with anti-proliferative and apoptosis inducing activity.

TETRAHYDROPYRIDOTHIOPHENES AS ANTRIPOLIFERATIVE AGENTS FOR THE TREATMENT OF CANCER

The invention relates to compounds of formula (I) wherein Ra is -C(O)ORI, in which R1 is 1-7C-a.kyl. 3-7C-cycoakyl, 1-7C-alkyl substituted by Raa, or 2-7C-alky substituted by Rab and Rac on different carbon atoms, Rb is -T-Q, in which T is 1-6C-alkylene or 3-7C-cycloalkylene, and Q is substituted by Rba and Rbb and Rbc, and is phenyl, wich are useful for the therapy of hyperprolif erative diseases, in particular human cancer.