1040390-31-5

Basic information

• Product Name: (S)-tert-butyl 3-hydroxypent-4-enoate
• Synonyms: (S)-tert-butyl 3-hydroxypent-4-enoate;(3S)-3-Hydroxy-4-pentenoic acid tert-butyl ester
• CAS NO: 1040390-31-5
• Molecular Formula: C₉H₁₆O₃
• Molecular Weight: 172.22154
• Mol File: 1040390-31-5.mol
• Article Data: 14

Chemical Properties

• Boiling Point: 238℃
• Flash Point: 91℃
• Appearance: /
• Density: 0.992
• CAS DataBase Reference: (S)-tert-butyl 3-hydroxypent-4-enoate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 3-hydroxypent-4-enoate(1040390-31-5)
• EPA Substance Registry System: (S)-tert-butyl 3-hydroxypent-4-enoate(1040390-31-5)

Safety Data

• Hazardous Substances Data: 1040390-31-5(Hazardous Substances Data)

Usage

General Description

(S)-tert-butyl 3-hydroxypent-4-enoate, also known as (S)-t-butyl 3-hydroxypent-4-enoate, is a chemical compound with the molecular formula C10H18O3. It is a derivative of t-butyl hydroxy ester and is commonly used as a building block in organic synthesis. (S)-tert-butyl 3-hydroxypent-4-enoate is a clear, colorless liquid with a fruity odor, and it is soluble in organic solvents. (S)-tert-butyl 3-hydroxypent-4-enoate is often used in the production of flavors and fragrances, as well as in the pharmaceutical industry for the synthesis of various compounds. Additionally, it can serve as a chiral building block in the synthesis of complex molecules and pharmaceutical intermediates.

Upstream product

• 172516-15-3 (3S)-3-acetoxy-4-pentenoic acid tert-butyl ester 
• 108-05-4 vinyl acetate 
• 122763-67-1 tert-butyl 3-hydroxypent-4-enoate 
• 1207973-75-8 lithium tert-butyl acetate 
• 220861-37-0 (R)-tert-butyl 3-hydroxypent-4-enoate 
• 540-88-5 acetic acid tert-butyl ester 

Downstream Products

• 172516-16-4 (S)-3-(tert-Butyl-diphenyl-silanyloxy)-pent-4-enoic acid tert-butyl ester 
• 172516-17-5 (S)-3-((tert-butyldiphenylsilyl)oxy)pent-4-enal 
• 167892-85-5 (4R,6S)-6-(tert-Butyl-diphenyl-silanyloxy)-oct-7-en-1-yn-4-ol 
• 172516-14-2 C₃₀H₄₄O₂Si₂ 
• 172516-18-6 (5R,7S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-non-8-en-2-yn-1-ol 
• 172516-19-7 (Z)-(5S,7S)-5-(tert-Butyl-dimethyl-silanyloxy)-7-(tert-butyl-diphenyl-silanyloxy)-3-iodo-nona-2,8-dien-1-ol 

Relevant articles and documents

A Chiral Building Block for the Stereocontrolled Installation of the 1,3-Diol Motif

A new chiral building block for the direct installation of the 1,3-diol motif is presented. Aldehyde olefination followed by directed reduction allows for the synthesis of both the syn- and the anti-configured diol in a fully stereocontrolled way. The building block was used for the total synthesis of naturally occurring 1,2,4-trihydroxynonadecanes starting from pentadecanal.

A stereocontrolled synthesis of the hydrophobic moiety of rhamnolipids

A new approach toward the synthesis of the hydrophobic moiety of rhamnolipid derivatives has been developed, involving two key cross-metatheses and an unusual Mitsunobu reaction. Small structural variations of the side chains should enable a better understanding of the role of the lipid moiety in immunostimulatory and plant defense eliciting properties.

Synthesis of the C1-C13 fragment of biselyngbyaside

An advanced intermediate vinyl iodide corresponding to the C1-C13 fragment of the macrolide biselyngbyaside was prepared by a cross-metathesis reaction between vinyl alcohol and -alkene building blocks. The latter fragment, containing two stereocenters, w