104115-44-8Relevant articles and documents
Paukstelis,Kao
, p. 4783 (1972)
Acyl acid derivative and preparation method and medical application thereof
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Paragraph 0428-0432, (2020/07/02)
The invention relates to an acyl acid derivative as well as a preparation method and medical application thereof. Specifically, the invention relates to a compound represented by a general formula (I), a pharmaceutically acceptable salt thereof, or a pharmaceutical composition containing the same, and the invention also relates to a use thereof as an active ingredient in the prevention and/or treatment of muscle atrophy-related diseases, including myogenic muscle atrophy, disuse muscle atrophy, senile muscle atrophy, neurogenic muscle atrophy, and a use in the prevention and/or treatment of obesity, fatty liver, cardiovascular and cerebrovascular diseases, metabolic diseases, and anti-aging, wherein the definition of each group in the general formula (I) is the same as the definition in the specification.
NOVEL COMPOUNDS
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Page/Page column 53, (2015/12/17)
Disclosed are novel retinoid-related orphan receptor gamma (RORγ) modulators and their use in the treatment of diseases mediated by RORγ.
Direct enantioselective bronsted acid catalyzed N-acyliminium cyclization cascades of tryptamines and ketoacids
Holloway, Chloe A.,Muratore, Michael E.,Storer, R. Lan,Dixon, Darren J.
supporting information; experimental part, p. 4720 - 4723 (2010/12/25)
A direct enantio- and diastereoselective N-acyliminium cyclization cascade through chiral phosphoric acid catalyzed condensation of tryptamines with γ- and δ-ketoacid derivatives to provide architecturally complex heterocycles has been developed. The reac