10425-05-5Relevant articles and documents
Synthesis of Aryl Ketones by the Pd-Catalyzed C-H Activation of Arenes and Intermolecular Carbopalladation of Nitriles
Zhou, Chengxiang,Larock, Richard C.
, p. 2302 - 2303 (2004)
The palladium-catalyzed reaction of simple arenes and nitriles provides good to excellent yields of aryl ketones or the corresponding hindered imines. The addition of a small amount of DMSO increases the yields dramatically. Both intermolecular and intramolecular examples of this process are successful. This novel chemistry is believed to involve palladium-catalyzed C?H activation, followed by carbopalladation of the nitrile. Copyright
Water-Tolerant ortho-Acylation of Phenols
Dong, Shuang-Feng,Gao, Zhi-Yuan,He, Yu,Liu, Xu,Loh, Teck-Peng,Tian, Jie-Sheng,Wu, Peng
supporting information, p. 6594 - 6598 (2021/09/02)
A metal-free, water-tolerant, and one-pot process for ortho-acylation of phenols promoted by the iodine source/hydrogen peroxide system has been developed. This transformation undergoes ether formation, iodocyclization, C-C bond cleavage, and oxidative hydrolysis in a one-step manner, which is supported by control experiments.
Photo-Fries rearrangement in flow under aqueous micellar conditions
Chen, Chun-Jen,Chien, Chia-Chen,Kao, Shih-Chieh,Wu, Yen-Ku
, p. 15470 - 15472 (2020/12/25)
A flow edition of photo-Fries rearrangement for the synthesis of 2-acylphenols in an aqueous micellar medium has been described. We take advantage of a narrow channel reactor and micelle-induced confinement effect to refine both the efficiency and selectivity of the parent photoreaction. This journal is