104306-59-4

Basic information

• Product Name: 2-{Hydroxy-[4-(4-methoxy-phenyl)-cyclohex-3-enyl]-methylene}-malonic acid diethyl ester
• CAS NO: 104306-59-4
• Molecular Weight: 374.434
• Mol File: 104306-59-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-{Hydroxy-[4-(4-methoxy-phenyl)-cyclohex-3-enyl]-methylene}-malonic acid diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{Hydroxy-[4-(4-methoxy-phenyl)-cyclohex-3-enyl]-methylene}-malonic acid diethyl ester(104306-59-4)
• EPA Substance Registry System: 2-{Hydroxy-[4-(4-methoxy-phenyl)-cyclohex-3-enyl]-methylene}-malonic acid diethyl ester(104306-59-4)

Safety Data

• Hazardous Substances Data: 104306-59-4(Hazardous Substances Data)

Upstream product

• 49708-14-7 4-(4-methoxy-phenyl)-cyclohex-3-enecarboxylic acid 
• 105-53-3 diethyl malonate 
• 35227-78-2 diethyl (ethoxymagnesio)malonate 
• 104306-58-3 4-(4-Methoxy-phenyl)-cyclohex-3-enecarbonyl chloride 

Downstream Products

• 104306-61-8 4-p-methoxyphenylbicyclo(2.2.2)octane-2,3-dione 
• 79674-03-6 4-(4-Methoxy-phenyl)-cyclohex-3-enecarboxylic acid methyl ester 
• 104306-60-7 4-p-methoxyphenylbicyclo<2.2.2>octan-2-one 
• 13021-18-6 1-(4'-methoxy-biphenyl-4-yl)-ethanone 

Relevant articles and documents

CONDENSED CYCLIC AND BRIDGED-RING SYSTEMS : PART 12. A NOVEL SYNTHETIC ROUTE TO 4-p-METHOXYPHENYL-BICYCLOOCTAN-2-ONES AND SOME BICYCLOOCTANE DERIVATIVES BY ACID-CATALYZED INTRAMOLECULAR C-ALKYLATION AND REARRANGEMENT REACTIONS.

The efficacy of a new acid-catalyzed intramolecular C-alkylation has been demonstrated by the synthesis of 1-methyl-4-p-methoxyphenylbicyclooctan-2-one (5) and 4-p-methoxy-phenylbicyclooctan-2-one (6) from easily accessible starting material