10437-85-1

Basic information

• Product Name: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER
• Synonyms: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER;Cyclobutanol, 1-(4-Methylbenzenesulfonate);cyclobutyl 4-methylbenzenesulfonate
• CAS NO: 10437-85-1
• Molecular Formula: C₁₁H₁₄O₃S
• Molecular Weight: 226.29
• Mol File: 10437-85-1.mol
• Article Data: 7

Chemical Properties

• Appearance: /
• CAS DataBase Reference: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER(10437-85-1)
• EPA Substance Registry System: TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER(10437-85-1)

Safety Data

• Hazardous Substances Data: 10437-85-1(Hazardous Substances Data)

Usage

Description

TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER is a chemical compound that consists of toluene-4-sulfonic acid and cyclobutyl ester. It is recognized for its strong acid catalytic properties and its ability to function as a nucleophile in organic reactions. This versatile chemical is widely used in the field of organic chemistry.

Uses

Used in Pharmaceutical Industry:
TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER is used as a reagent for various chemical synthesis processes, particularly in the pharmaceutical industry. It aids in the production of a variety of pharmaceutical drugs and biologically active molecules due to its strong acid catalytic properties and its ability to act as a nucleophile.
Used in Agrochemical Industry:
In the agrochemical industry, TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER is also utilized as a reagent in chemical synthesis processes. Its strong acid catalytic properties and nucleophilic capabilities contribute to the development of agrochemical products.
Used in Organic Chemistry:
TOLUENE-4-SULFONIC ACID CYCLOBUTYL ESTER is used as a building block in the synthesis of various organic compounds. Its versatility in acting as both a strong acid catalyst and a nucleophile makes it a valuable component in organic chemistry for creating a range of molecules with different applications.

Upstream product

• 2919-23-5 cyclobutanol 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 6861-61-6 cyclobutane thiol 
• 822-35-5 cyclobutene 
• 144773-93-3 1,5-dibromocyclopentene 
• 86488-28-0 (+/-)-2-bromocyclopent-2-enol 
• 53911-82-3 (cyclopropylmethyl)(phenyl)sulfane 
• 67132-84-7 cyclobutyl phenyl sulfide 
• 4285-49-8 homoallyl phenyl sulfide 
• 885267-05-0 (2-bromophenyl)(cyclobutyl)sulfane 

Relevant articles and documents

SUBSTITUTED OXOPYRIDINE DERIVATIVES

The invention relates to substituted oxopyridine derivatives and to processes for their preparation, and also to their use for preparing medicaments for the treatment and/or prophylaxis of diseases, in particular vascular disorders, preferably thrombotic

Compounds Having CRTH2 Antagonist Activity

Compounds of general formula (I) wherein W is chloro or fluoro; Z is a group SO2R1; wherein R1 is —C3-C8 cycloalkyl or heterocyclyl optionally substituted with one or more substituents chosen from hal

Dynamic models for the thermal deazetization of 2,3-diazabicyclo[2.2.1]hept-2-ene

Kinetic studies on the thermal nitrogen extrusion from 2,3-diazabicyclo[2.2.1]hept-2-ene-exo,exo-5,6-d2 are reported. The ratio of rate constants for formation of the label-isomeric products (bicyclo[2.1.0]pentane-exo,exo-2,3-d2 and -endo,endo-2,3-d2) is found to exhibit no statistically significant temperature dependence. A comparison of gas-phase and solution-phase results is presented. The results are interpreted in terms of two complementary dynamic models. In the first, classical trajectory calculations are run on a three-dimensional projection (two geometric coordinates) of the potential energy hypersurface. These calculations correctly identify the major product, and reproduce the near temperature-independence of the rate-constant ratio, but do not match the ratio quantitatively. Modification of the trajectory calculations to simulate the effect of collisions with solvent molecules also qualitatively matches the observed difference between gas-phase and solution-phase behavior. In the second model, the vector of atomic displacements corresponding to the reaction coordinate at the transition state for nitrogen loss is identified by both semiempirical and ab initio calculations. The components of this vector pointing along the paths to the post-transition-state minima are computed and are shown to lead to a prediction of the product ratio that is in good (if partly fortuitous) agreement with the experimental result. The vector model is used to predict isotope effects on the product ratio, which are then investigated experimantally with 2,3-diazabicyclo[2.2.1]hept-2-ene-endo,endo-1,4,5,6,7,7-d6 and -endo-7-d.