1046478-47-0

Basic information

• Product Name: 1-benzyl-4-(furan-3-yl)-1,2,3,6-tetrahydropyridine
• Synonyms: 1-benzyl-4-(furan-3-yl)-1,2,3,6-tetrahydropyridine
• CAS NO: 1046478-47-0
• Molecular Weight: 239.317
• Mol File: 1046478-47-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-benzyl-4-(furan-3-yl)-1,2,3,6-tetrahydropyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-benzyl-4-(furan-3-yl)-1,2,3,6-tetrahydropyridine(1046478-47-0)
• EPA Substance Registry System: 1-benzyl-4-(furan-3-yl)-1,2,3,6-tetrahydropyridine(1046478-47-0)

Safety Data

• Hazardous Substances Data: 1046478-47-0(Hazardous Substances Data)

Upstream product

• 22037-28-1 3-bromofurane 
• 3612-20-2 1-phenylmethyl-4-piperidone 

Relevant articles and documents

Pd-catalyzed cross-coupling reactions with carbonyls: Application in a very efficient synthesis of 4-aryltetrahydropyridines

A method is proposed to prepare 4-aryltetrahydropyridines by a Pd-catalyzed cross-coupling reaction by using tosylhydrazone as the nucleophilic coupling agent without stoichiometric organometallic reagent. Palladium-catalyzed couplings can be used for the formation of C-C linkages. It was observed during study that tosylhydrazone can be generated by employing 4-piperidones directly in the cross-coupling reaction with tetrahydropyridines in very high yields. It was also found during study that the ketones and aldehydes can be employed as nucleophilic coupling partners in a reaction without using stoichiometric organometallic reagent. The study concluded that the method can be used to prepare different types of di- and trisubstituted olefins at large scale.