105168-92-1Relevant articles and documents
SULFONANILIDE ANALOGS AS SELECTIVE AROMATASE MODULATORS
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Page/Page column title page; 18; 1/15, (2010/11/28)
Compounds and methods suppressing aromatase activity expression in cancer cells. Provided are compounds are those of formula I: wherein R1 may be alkyl, cycloakyl, haloalkyl, aryl, substituted aryl, haloaryl, alkoxy, alkylaryl, and arylalkyl; R2 is H, alk
Novel sulfonanilide analogues suppress aromatase expression and activity in breast cancer cells independent of COX-2 inhibition
Su, Bin,Diaz-Cruz, Edgar S.,Landini, Serena,Brueggemeier, Robert W.
, p. 1413 - 1419 (2007/10/03)
Aromatase is a particularly attractive target in the treatment of estrogen receptor positive breast cancer. Aromatase levels in breast cancer cells are enhanced by prostaglandins and reduced by COX inhibitors. The synthesis and biological evaluation of a