105356-57-8 Usage
General Description
4-Thien-2-yl-2,4-dioxobutanoic acid is a chemical compound with the molecular formula C8H8O4S. It is a derivative of thien-2-yl and 2,4-dioxobutanoic acid and is known for its potential applications in pharmaceutical and organic chemistry. It is a white to off-white solid with a molecular weight of 184.21 g/mol and a melting point of 122-124°C. The compound is a thien-2-yl derivative of alpha-ketoglutaric acid, which is an intermediate in the citric acid cycle. It is used as a building block in the synthesis of various pharmaceutical compounds and organic molecules. However, further research and testing are needed to fully understand its potential uses and properties.
Check Digit Verification of cas no
The CAS Registry Mumber 105356-57-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,3,5 and 6 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 105356-57:
(8*1)+(7*0)+(6*5)+(5*3)+(4*5)+(3*6)+(2*5)+(1*7)=108
108 % 10 = 8
So 105356-57-8 is a valid CAS Registry Number.
InChI:InChI=1/C8H6O4S/c9-5(4-6(10)8(11)12)7-2-1-3-13-7/h1-3H,4H2,(H,11,12)
105356-57-8Relevant articles and documents
The identification and optimization of 2,4-diketobutyric acids as flap endonuclease 1 inhibitors
Tumey, L. Nathan,Huck, Bayard,Gleason, Elizabeth,Wang, Jianmin,Silver, Daniel,Brunden, Kurt,Boozer, Sherry,Rundlett, Stephen,Sherf, Bruce,Murphy, Steven,Bailey, Andrew,Dent, Tom,Leventhal, Christina,Harrington, John,Bennani, Youssef L.
, p. 4915 - 4918 (2007/10/03)
Flap endonuclease 1 (FEN1) is a key enzyme involved in base excision repair (BER), a primary pathway utilized by mammalian cells to repair DNA damage. In this report, we describe the identification and SAR of a series of 2,4-diketobutyric acid FEN1 inhibi
