10542-07-1Relevant articles and documents
The formation of dimethyl amino(pyrene-1-yl)methylphosphonates in the Kabachnik-Fields reaction with dibenzyl phosphite, pyrene-1-carboxaldehyde and a non-aromatic amine in methanol
Lewkowski, Jaros?aw,Rodriguez Moya, Maria
, p. 713 - 718 (2017)
The Kabachnik-Fields reaction of pyrene-1-carboxaldehyde with dibenzyl phosphite and aliphatic amines in methanol led to the formation of dimethyl amino(pyren-1-yl)methyl-phosphonates, in some cases accompanied by dimethyl hydroxy(pyren-1-yl)methyl-phosphonate. These results are exclusive for the above compounds, in all other studied cases (aromatic aldehydes, aromatic amines) the mixtures of several aminophosphonates were obtained.
Method and compositions for identifying anti-HIV therapeutic compounds
-
, (2008/06/13)
Methods are provided for identifying anti-HIV therapeutic compounds substituted with carboxyl ester or phosphonate ester groups. Libraries of such compounds are screened optionally using the novel enzyme GS-7340 Ester Hydrolase. Compositions and methods relating to GS-7340 Ester Hydrolase also are provided.
Degradation of n-Butylaminocyclohexyl phosphonic Acid di-n-Butylester (Buminafos) in Aqueous Medium
Schneider, B.,Porzel, A.,Weidhase, R.,Schuette, H. R.
, p. 85 - 90 (2007/10/02)
In aqueous medium, breakdown of Buminafos (1) is connected with total loss of its herbicidal activity.The phosphorus-carbon bond is cleaved and n-butylcyclohexylidene amine (3), cyclohexanone (5), phosphoric acid mono-n-butyl ester (4) (partly as n-butylamine salt), and 1-aminocyclohexyl phosphonic acid di-n-butylester (8) were found as degradation products of carbon-14 labeled Buminafos.Identification was performed by MS, GC/MS, 1H- and 31P-n.m.r. spectroscopy, by detection of phosphorus, and by means of the radioactivity.
