1054483-78-1 Usage
Description
2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE is a chemical compound characterized by its unique molecular structure, which features a pyridine ring with a hydroxyl group at the 2nd position and a tetramethyl-1,3,2-dioxaborolan-2-yl group at the 5th position. 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE is known for its potential applications in various chemical and pharmaceutical processes due to its reactive functional groups.
Uses
Used in Pharmaceutical Industry:
2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE is used as a key intermediate in the synthesis of modified C3 Betulinic acid (B330250) derivatives, which serve as HIV maturation inhibitors. These derivatives have the potential to disrupt the life cycle of the HIV virus, thereby providing a therapeutic approach to combat the disease.
Used in Chemical Synthesis:
2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE is used as a reactant in the synthesis of novel glutamate transporter EAAT2 activators. These activators play a crucial role in modulating the activity of EAAT2, which is involved in the regulation of glutamate levels in the brain. 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE contributes to the development of potential treatments for neurological disorders associated with glutamate dysregulation.
Used in Drug Development:
6-Hydroxypyridine-3-boronic acid pinacol ester, a derivative of 2-HYDROXY-5-(4,4,5,5-TETRAMETHYL-1,3,2-DIOXABOROLAN-2-YL)PYRIDINE, is used in the preparation of crizotinib derivatives as SHIP2 inhibitors. SHIP2 inhibitors are being investigated for their potential role in treating various diseases, including cancer, by modulating cellular signaling pathways. The development of these inhibitors could lead to novel therapeutic strategies for a range of medical conditions.
Check Digit Verification of cas no
The CAS Registry Mumber 1054483-78-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,5,4,4,8 and 3 respectively; the second part has 2 digits, 7 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1054483-78:
(9*1)+(8*0)+(7*5)+(6*4)+(5*4)+(4*8)+(3*3)+(2*7)+(1*8)=151
151 % 10 = 1
So 1054483-78-1 is a valid CAS Registry Number.
