105492-12-4 Usage
General Description
3-PHENYL-1H-INDOLE-2-CARBOHYDRAZIDE, also known as phenylindole carbohydrazide, is a chemical compound with the molecular formula C15H14N4O. It is a white to off-white solid that is insoluble in water but soluble in organic solvents such as dimethyl sulfoxide and ethanol. 3-PHENYL-1H-INDOLE-2-CARBOHYDRAZIDE is commonly used in organic synthesis and pharmaceutical research as a building block for various heterocyclic compounds and potential drug candidates. It has also shown potential antitumor and antimicrobial activity in preliminary studies, making it a promising candidate for further research and development.
Check Digit Verification of cas no
The CAS Registry Mumber 105492-12-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,0,5,4,9 and 2 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 105492-12:
(8*1)+(7*0)+(6*5)+(5*4)+(4*9)+(3*2)+(2*1)+(1*2)=104
104 % 10 = 4
So 105492-12-4 is a valid CAS Registry Number.
InChI:InChI=1/C15H13N3O/c16-18-15(19)14-13(10-6-2-1-3-7-10)11-8-4-5-9-12(11)17-14/h1-9,17H,16H2,(H,18,19)
105492-12-4Relevant articles and documents
3-substituted indole antiproliferative angiogenesis inhibitors
-
, (2008/06/13)
3-Substituted indole carbohydrazides having the formula are useful for inhibiting angiogenesis and cell proliferation. Also disclosed are compositions which inhibit angiogenesis and cell proliferation and methods of inhibiting angiogenesis and cancer in a mammal.
Synthesis of Substituted 1,2,3,8-Tetrahydroindolobenzodiazepin-2-ones and 5,6,7,8-Tetrahydroindolobenzodiazepin-6-ones
Hiremath, Shivayogi P.,Badami, Prema S.,Purohit, Muralidhar G.
, p. 1115 - 1119 (2007/10/02)
Nitrosation (NaNO2/AcOH) of 2-phenylindoles (1a-d) and subsequent reduction of the resultant 3-nitroso-2-phenylindoles (2a-d) with sodium dithionite in alkali furnish the corresponding 3-aminoindoles (3a-d), which on condensation with ethyl chloroformate