106109-76-6

Basic information

• Product Name: Propanoic acid, 3-oxo-3-[[3-(trifluoromethyl)phenyl]amino]-, methyl ester
• CAS NO: 106109-76-6
• Molecular Formula: C11H10F3NO3
• Molecular Weight: 261.201
• Mol File: 106109-76-6.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 3-oxo-3-[[3-(trifluoromethyl)phenyl]amino]-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 3-oxo-3-[[3-(trifluoromethyl)phenyl]amino]-, methyl ester(106109-76-6)
• EPA Substance Registry System: Propanoic acid, 3-oxo-3-[[3-(trifluoromethyl)phenyl]amino]-, methyl ester(106109-76-6)

Safety Data

• Hazardous Substances Data: 106109-76-6(Hazardous Substances Data)

Upstream product

• 37517-81-0 3-chloro-3-oxopropanoic acid methyl ester 
• 98-16-8 3-trifluoromethylaniline 

Downstream Products

• 15386-85-3 3-oxo-3-{[3-(trifluoromethyl)phenyl]amino}propanoic acid 
• 850798-04-8 N-(2-chloro-1-oxy-pyridin-4-yl)-N'-(3-trifuoromethyl-phenyl)-malonamide 
• 850797-90-9 N-(2-chloro-pyridin-4-yl)-N'-(3-trifuoromethyl-phenyl)-malonamide 
• 850797-58-9 N-phenyl-N'-(3-trifuoromethyl-phenyl)-malonamide 
• 1060674-17-0 2-chloro-N₄-(4-methoxyphenyl)-7-(trifluoromethyl)quinoline-3,4-diamine 
• 1060673-50-8 3-[1-(4-Methoxy-phenyl)-7-trifluoromethyl-1H-imidazo[4,5-c]quinolin-4-ylamino]-propan-1-ol 
• 1060674-14-7 2-chloro-N-(4-methoxyphenyl)-3-nitro-7-(trifluoromethyl)quinolin-4-amine 
• 1060674-20-5 4-chloro-1-(4-methoxyphenyl)-7-(trifluoromethyl)-1 H-imidazo[4,5-c]quinoline 
• 1281969-56-9 3-(5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamido)-N,N,N-trimethylpropan-1-aminium acetate 
• 1281969-54-7 3-(5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamido)-N,N,N-trimethylpropan-1-aminium bromide 
• 1281969-55-8 5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-N-(3-(dimethylamino)propyl)-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 
• 1281969-57-0 3-(5-(1-(4-cyanophenyl)-1H-pyrazol-5-yl)-6-methyl-2-oxo-1-(3-(trifluoromethyl)phenyl)-1,2-dihydropyridine-3-carboxamido)-N,N,N-trimethylpropan-1-aminium benzenesulfonate 
• 1281969-58-1 N-[3-(dimethylamino)propyl]-5-iodo-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 
• 950857-36-0 5-iodo-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxylic acid 

Relevant articles and documents

ELASTASE INHIBITORS

Described herein are compounds, compositions, and methods of their use for the treatment of a lung or intestinal disease.

NOVEL SALT 628

6-Methyl-5-(1-methyl-1H-pyrazol-5-yl)-N-{[5-(methylsulfonyl)pyridin-2-yl]methyl}-2-oxo-1-[3-(trifluoromethyl)phenyl]-1,2-dihydropyridine-3-carboxamide 4-methylbenzenesulfonate and a novel crystalline form thereof are disclosed together with processes for preparing such salt and form, pharmaceutical compositions comprising such a salt and form, and the methods of treatment using such a salt and form.

SUBSTITUTED 2-ARYLMETHYLENE-N-ARYL-N'-ARYL-MALONAMIDES AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS

The present invention is directed to substituted 2-arylmethylene-N-aryl-N'-aryl-malonamides and analogs thereof. The present invention also relates to the discovery that the compounds are activators of caspases and inducers of apoptosis. Therefore, the activators os caspases and inducers of apoptosis of this invention can be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of anormal cells occurs.