106511-80-2

Basic information

• Product Name: methyl N-(2-methoxycarbonylphenyl)dithiocarbamate
• CAS NO: 106511-80-2
• Molecular Weight: 241.335
• Mol File: 106511-80-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: methyl N-(2-methoxycarbonylphenyl)dithiocarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-(2-methoxycarbonylphenyl)dithiocarbamate(106511-80-2)
• EPA Substance Registry System: methyl N-(2-methoxycarbonylphenyl)dithiocarbamate(106511-80-2)

Safety Data

• Hazardous Substances Data: 106511-80-2(Hazardous Substances Data)

Upstream product

• 75-15-0 carbon disulfide 
• 134-20-3 2-carbomethoxyaniline 
• 77-78-1 dimethyl sulfate 

Downstream Products

• 16951-33-0 3-amino-2-mercapto-3H-quinazolin-4-one 
• 623573-77-3 3-amino-2-benzylaminoquinazolin-4(3H)-one 
• 936501-61-0 C₆H₅CH₂C₉H₄N₄OCH₂Cl 

Relevant articles and documents

Development of thieno- and benzopyrimidinone inhibitors of the Hedgehog signaling pathway reveals PDE4-dependent and PDE4-independent mechanisms of action

From a high content in vivo screen for modulators of developmental patterning in embryonic zebrafish, we previously identified eggmanone (EGM1, 3) as a Hedgehog (Hh) signaling inhibitor functioning downstream of Smoothened. Phenotypic optimization studies for in vitro probe development utilizing a Gli transcription-linked stable luciferase reporter cell line identified EGM1 analogs with improved potency and aqueous solubility. Mechanistic profiling of optimized analogs indicated two distinct scaffold clusters: PDE4 inhibitors able to inhibit downstream of Sufu, and PDE4-independent Hh inhibitors functioning between Smo and Sufu. Each class represents valuable in vitro probes for elucidating the complex mechanisms of Hh regulation.

Synthesis, analgesic and anti-inflammatory activities of some novel 2,3-disubstituted quinazolin-4(3H)-ones.

A series of novel 2-benzylamino-3-substituted quinazolin-4(3H)-ones have been synthesized by treating 3-amino-2-benzylamino quinazolin-4(3H)-one, with different aldehydes and ketones. The starting material 3-amino-2-benzylamino quinazolin-4(3H)-one was sy

Synthesis and pharmacological investigation of some novel 2,3-disubstituted quinazolin-4(3H)-ones as analgesic and antiinflammatory agents

A series of novel 2-substituted quinazolin-4(3H)-ones have been synthesized by condensing the aromatic primary amine of 2-substituted quinazolines with different aldehydes and ketones. The synthesized compounds were confirmed by their spectral data (IR, N