1067653-57-9

Basic information

• Product Name: 6-chloro-3-[3-(4-chlorobenzyl)-5-phenyl-3H-imidazol-4-yl]-1H-indole
• Synonyms: 6-chloro-3-[3-(4-chlorobenzyl)-5-phenyl-3H-imidazol-4-yl]-1H-indole
• CAS NO: 1067653-57-9
• Molecular Weight: 418.325
• Mol File: 1067653-57-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 6-chloro-3-[3-(4-chlorobenzyl)-5-phenyl-3H-imidazol-4-yl]-1H-indole(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-3-[3-(4-chlorobenzyl)-5-phenyl-3H-imidazol-4-yl]-1H-indole(1067653-57-9)
• EPA Substance Registry System: 6-chloro-3-[3-(4-chlorobenzyl)-5-phenyl-3H-imidazol-4-yl]-1H-indole(1067653-57-9)

Safety Data

• Hazardous Substances Data: 1067653-57-9(Hazardous Substances Data)

Upstream product

• 703-82-2 6-chloro-1H-indole-3-carbaldehyde 
• 36635-66-2 α-tosylbenzyl isocyanide 
• 104-86-9 4-chlorobenzylamine 

Relevant articles and documents

3-IMIDAZOLYL-INDOLES FOR THE TREATMENT OF PROLIFERATIVE DISEASES

The invention relates to 3-heterocyclyl indolyl compounds capable of inhibiting the interaction between p53, or variants thereof, and MDM2 and/or MDM4, or variants thereof, respectively, said compounds having the formula (I) wherein R1, R2, R3, R4, RA, Y and Y are as defined in the specification. Due to their activity, the compounds are useful in the treatment of various disorders and diseases mediated by the activity of MDM2 and/or MDM4, or variants thereof, such as inflammatory or proliferative diseases or in the protection of cells.