1071435-62-5 Usage
Description
(S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine is a complex organic chemical compound characterized by a pyridine ring with a trifluoromethyl substitution and an amine functional group. (S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine belongs to the class of amines, which are known for their diverse applications in various industries. The trifluoromethyl group, a strong electron withdrawing group, and the specific (S)-stereochemistry contribute to the compound's unique properties and potential utility in pharmaceutical and agrochemical applications.
Uses
Used in Pharmaceutical Industry:
(S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine is used as a building block for the synthesis of various pharmaceutical compounds due to its unique structure and properties. The presence of the trifluoromethyl group and the amine functional group allows for the creation of new molecules with potential therapeutic applications.
Used in Agrochemical Industry:
(S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine is used as a precursor in the development of agrochemicals, such as pesticides and herbicides. (S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine's electron withdrawing properties and stereochemistry can be exploited to design molecules with enhanced biological activity and selectivity, leading to more effective and targeted agrochemical products.
Used in Chemical Research:
(S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine serves as a valuable research tool in the field of organic chemistry. Its unique structure and properties make it an interesting subject for studying reaction mechanisms, exploring new synthetic routes, and understanding the relationship between molecular structure and biological activity.
Used in Material Science:
(S)-1-(6-(Trifluoromethyl)pyridin-3-yl)ethanamine's electron withdrawing trifluoromethyl group and amine functional group may also find applications in the development of new materials with specific properties, such as improved conductivity, stability, or reactivity. This can be particularly useful in the fields of electronics, energy storage, and advanced materials.
Check Digit Verification of cas no
The CAS Registry Mumber 1071435-62-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,0,7,1,4,3 and 5 respectively; the second part has 2 digits, 6 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1071435-62:
(9*1)+(8*0)+(7*7)+(6*1)+(5*4)+(4*3)+(3*5)+(2*6)+(1*2)=125
125 % 10 = 5
So 1071435-62-5 is a valid CAS Registry Number.
1071435-62-5Relevant articles and documents
Asymmetric Biocatalytic Synthesis of Fluorinated Pyridines through Transesterification or Transamination: Computational Insights into the Reactivity of Transaminases
López-Iglesias, María,González-Martínez, Daniel,Rodríguez-Mata, María,Gotor, Vicente,Busto, Eduardo,Kroutil, Wolfgang,Gotor-Fernández, Vicente
, p. 279 - 291 (2017)
The synthesis of a family of pyridines bearing a fluorinated substituent on the aromatic ring has been carried out through two independent and highly stereoselective chemoenzymatic strategies. Short chemical synthetic routes toward fluorinated racemic amines and prochiral ketones have been developed, which served as substrates to explore the suitability of lipases and transaminases in asymmetric biotransformations. The lipase-catalyzed kinetic resolution via acylation of racemic amines proceeded smoothly giving conversions close to 50% and excellent enantioselectivities. Alternatively, the biotransamination of the corresponding prochiral ketones was investigated giving access to both optically pure amine enantiomers using transaminases with complementary selectivity. High to quantitative conversion values were achieved, which allowed the isolation of the amines in moderate to high yields (40–88%). A deeper understanding of the latter process was enabled by performing theoretical calculations on thermodynamic and mechanistic aspects. Calculations showed that the biotransamination reactions are highly favoured by the presence of fluorine atoms and the pyridine ring. (Figure presented.).
PYRID-2-YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF
-
, (2008/12/04)
Fused heterocyclic compounds are provided according to formula 1a or 1b: where R1, R2, and R3 are as defined herein. Provided compounds and pharmaceutical compositions thereof are useful for the prevention and treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, pain, inflammation, cognitive disorders, anxiety, depression, and others.
