107274-76-0

Basic information

• Product Name: 4-(6-chloroquinolin-2-yl)-N,N-dimethylaniline
• Synonyms: 4-(6-chloroquinolin-2-yl)-N,N-dimethylaniline
• CAS NO: 107274-76-0
• Molecular Weight: 282.772
• Mol File: 107274-76-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-(6-chloroquinolin-2-yl)-N,N-dimethylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-chloroquinolin-2-yl)-N,N-dimethylaniline(107274-76-0)
• EPA Substance Registry System: 4-(6-chloroquinolin-2-yl)-N,N-dimethylaniline(107274-76-0)

Safety Data

• Hazardous Substances Data: 107274-76-0(Hazardous Substances Data)

Upstream product

• 1810-72-6 2,6-dichloroquinoline 
• 7353-91-5 4-dimethylaminophenylmagnesium bromide 

Relevant articles and documents

Chemoselective chromium(II)-catalyzed cross-coupling reactions of dichlorinated heteroaromatics with functionalized aryl Grignard reagents

Chromium(II) chloride catalyzes the chemoselective cross-coupling reaction of dichloropyridines with a range of functionalized (hetero)aromatic Grignard reagents at room temperature. Functional groups, such as esters and acetals, are well tolerated in this transformation. Previously challenging substrates, quinolines and isoquinolines, participate in the selective Cr-catalyzed cross-coupling in cyclopentyl methyl ether (CPME) as the solvent. The effective purging of Cr salts is demonstrated by using various solid supports.