1073126-84-7Relevant articles and documents
Fabrication of organogels achieved by prodrug-based organogelators of ketoprofen
Mahire, Rahul R.,Agrawal, Deepika S.,Patil, Devanand K.,More, Dhananjay H.
, p. 33286 - 33291 (2014)
The treatment strategy of curing diseases using prodrugs of an anti-inflammatory drug is widespread. In the present study, we report on the synthesis of prodrugs of ketoprofen, consisting of a derivatization of ketoprofen and long hydrocarbon chain of fat
PHTHALIMIDE DERIVATIVES OF NON-STEROIDAL ANTI-INFLAMMATORY COMPOUNDS AND/OR TNF-ALPHA MODULATORS, METHOD FOR PRODUCING SAME, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME AND USES THEREOF FOR THE TREATMENT OF INFLAMMATORY DISEASES
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, (2012/05/20)
The present invention relates to phthalimide derivatives of non-steroidal and/or TNF-α modulating anti-inflammatory compounds as well as the process of obtaining the so-called derivatives, pharmaceutical compositions containing such derivatives and their uses, including use in the treatment of inflammatory diseases, especially those related to chronic inflammatory processes, such as rheumatoid arthritis and intestinal inflammatory diseases (for instance, Chron's disease) and the use of the referred to pharmaceutical compositions as antipyretic, analgesic and platelet antiaggregating medications.
Synthesis and pharmacological evaluation of imidazole derivatives of some non-steroidal anti-inflammatory drugs
Parcha, Versha,Kaur, Jaswinder,Gupta, Vinay,Anroop
experimental part, p. 321 - 325 (2009/06/25)
A series of imidazole derivatives of NSAIDs (4a-l) have been prepared by condensation of NSAIDs hydrazides (1,2) with substituted oxazolones and evaluated for anti-inflammatory and gastrointestinal toxicity, which showed good anti-inflammatory activity and reduced gastrointestinal toxicity as compared to parent drug.