1073968-33-8Relevant articles and documents
A Tandem Approach to Functionalized Carbazoles from Indoles via Two Successive Regioselective Oxidative Heck Reactions Followed by Thermal Electrocyclization
Laha, Joydev K.,Dayal, Neetu
, p. 4742 - 4745 (2015)
A direct one-pot approach to the synthesis of carbazoles (mono-, di-, and trisubstituted) and α-carbolines from readily available indoles or 7-azaindoles and alkenes is described. Based on mechanistic studies, the tandem reaction follows the sequence: pal
Oxidative Pd(II)-catalyzed C-H bond amination to carbazole at ambient temperature
Jordan-Hore, James A.,Johansson, Carin C. C.,Gulias, Moises,Beck, Elizabeth M.,Gaunt, Matthew J.
supporting information; experimental part, p. 16184 - 16186 (2009/05/08)
We report a new Pd(II)-catalyzed C-H bond amination reaction to form carbazoles, an important motif that is prevalent in a range of systems. The catalytic amination process operates under extremely mild conditions and produces carbazole products in good to excellent yields. Carbazoles possessing complex molecular architecture can also be formed using this reaction, highlighting its potential in natural product synthesis applications. Preliminary mechanistic investigations reveal the reaction proceeds through a Pd(II)/Pd(IV) manifold and that reductive elimination from a high oxidation state Pd(IV) complex facilitates the mild conditions of this transformation. Copyright
