107589-98-0

Basic information

• Product Name: 3β-Glycocholic Acid
• Synonyms: 3β-Glycocholic Acid;3β-N-Choloylglycine;N-[(3β,5β,7α,12α)-3,7,12-Τrihydroxy-24-oxocholan-24-yl]glycine;RFDAIACWWDREDC-ACZMRKGOSA-N
• CAS NO: 107589-98-0
• Molecular Formula: C₂₆H₄₃NO₆
• Molecular Weight: 465.62272
• Product Categories: Intermediates & Fine Chemicals;Metabolites & Impurities;Pharmaceuticals;Steroids;Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids
• Mol File: 107589-98-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• Stability: Hygroscopic
• CAS DataBase Reference: 3β-Glycocholic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 3β-Glycocholic Acid(107589-98-0)
• EPA Substance Registry System: 3β-Glycocholic Acid(107589-98-0)

Safety Data

• Hazardous Substances Data: 107589-98-0(Hazardous Substances Data)

Usage

Uses

Cholenoic acid present in significant proportions during early gastation.

Upstream product

• 863-57-0 sodium glycocholate 
• 88725-38-6 [(R)-4-((5R,7R,8R,9S,10S,12S,13R,14S,17R)-7,12-Dihydroxy-10,13-dimethyl-3-oxo-hexadecahydro-cyclopenta[a]phenanthren-17-yl)-pentanoylamino]-acetic acid 

Relevant articles and documents

Enzymatic α/β Inversion of C-3 Hydroxyl of Bile Acids and Study of the Effects of Organic Solvents on Reaction Rates

Enzymatic α/β inversion of the C-3 hydroxyl of numerous bile acids containing different numbers of hydroxyl groups in the skeleton and side chains of different lengths has been carried out.Inversion was obtained in two steps through the sequential use of the commercial enzymes 3α- and 3β-hydroxysteroid dehydrogenase, employed in the free form or immobilized on Eupergit C.The transformations were practically quantitative and the products more than 98percent pure.NAD was regenerated in situ with the pyruvate/lactic dehydrogenase system and NADH with the formate/formate dehydrogenase system.The effects of product inhibition on reaction rates and the favorable effects produced by low concentrations (7-10percent, v/v) of ethyl acetate and ethanol were also examined.