1076228-22-2

Basic information

• Product Name: (3S,4S)-1-[amino(oxo)acetyl]-N-((1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl)-3-(4-fluoro-2-methylphenyl)-N-methylpiperidine-4-carboxamide
• Synonyms: (3S,4S)-1-[amino(oxo)acetyl]-N-((1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl)-3-(4-fluoro-2-methylphenyl)-N-methylpiperidine-4-carboxamide
• CAS NO: 1076228-22-2
• Molecular Weight: 561.5
• Mol File: 1076228-22-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (3S,4S)-1-[amino(oxo)acetyl]-N-((1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl)-3-(4-fluoro-2-methylphenyl)-N-methylpiperidine-4-carboxamide(CAS DataBase Reference)
• NIST Chemistry Reference: (3S,4S)-1-[amino(oxo)acetyl]-N-((1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl)-3-(4-fluoro-2-methylphenyl)-N-methylpiperidine-4-carboxamide(1076228-22-2)
• EPA Substance Registry System: (3S,4S)-1-[amino(oxo)acetyl]-N-((1S)-1-[3,5-bis(trifluoromethyl)phenyl]ethyl)-3-(4-fluoro-2-methylphenyl)-N-methylpiperidine-4-carboxamide(1076228-22-2)

Safety Data

• Hazardous Substances Data: 1076228-22-2(Hazardous Substances Data)

Upstream product

• 30897-90-6 (2-methyl-4-fluorophenyl)magnesium bromide 
• 414910-08-0 (1S)-1-[3,5-bis(trifluoromethyl)phenyl]-N-methylethanamine hydrochloride 
• 1357586-70-9 (3S,4S)-1-(tert-butoxycarbonyl)-3-(4-fluoro-2-methylphenyl)piperidine-4-carboxylic acid (S)-1-phenylethylamine complex 
• 40175-06-2 ethyl 1-methyl-1,2,5,6-tetrahydropyridine-4-carboxylate 
• 471-47-6 oxamic acid 
• 1076230-22-2 (3S,4S)-3-(4-fluoro-2-methylphenyl)piperidine-4-carboxylic acid [(S)-1-(3,5-bistrifluoromethylphenyl)ethyl]methylamide hydrochloride 
• 4595-61-3 pyrimidine-5-carboxylic acid 

Relevant articles and documents

Novel 3-phenylpiperidine-4-carboxamides as highly potent and orally long-acting neurokinin-1 receptor antagonists with reduced CYP3A induction

The synthesis and biological evaluation of a series of novel 3-phenylpiperidine-4-carboxamide derivatives are described. These compounds are generated by hybridization of the substructures from two types of tachykinin NK1 receptor antagonists.