107659-70-1

Basic information

• Product Name: (4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one
• Synonyms: 1,3-Dioxolan-2-one, 4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-, rel-(4S,5R)-
• CAS NO: 107659-70-1
• Molecular Formula: C₁₈H₁₃Cl₂N₃O₃
• Molecular Weight: 390.2201
• Mol File: 107659-70-1.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 610.7°C at 760 mmHg
• Flash Point: 323.1°C
• Density: 1.48g/cm³
• Vapor Pressure: 7.45E-15mmHg at 25°C
• Refractive Index: 1.675
• CAS DataBase Reference: (4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one(CAS DataBase Reference)
• NIST Chemistry Reference: (4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one(107659-70-1)
• EPA Substance Registry System: (4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one(107659-70-1)

Safety Data

• Hazardous Substances Data: 107659-70-1(Hazardous Substances Data)

Usage

Description

(4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one is a complex organic molecule characterized by a dioxolane ring and a triazole moiety. It belongs to the class of antifungal agents and is utilized in the treatment of various fungal infections. The presence of the 1,2,4-triazol-1-ylmethyl group indicates its potential role as an inhibitor of fungal cytochrome P-450 enzymes, which are vital for the synthesis of ergosterol, a critical component of fungal cell membranes. (4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one's specific (4S,5R)-stereocenter is likely to contribute to its biological activity, and further research into its pharmacological properties and potential therapeutic applications is encouraged.

Uses

Used in Pharmaceutical Industry:
(4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one is used as an antifungal agent for the treatment of various fungal infections. Its application is based on its ability to inhibit fungal cytochrome P-450 enzymes, which are essential for the synthesis of ergosterol, a key component of fungal cell membranes.
Used in Research and Development:
In the field of pharmaceutical research and development, (4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one serves as a valuable compound for studying the mechanisms of action against fungal infections. Its specific stereochemical configuration and the presence of the 1,2,4-triazol-1-ylmethyl group make it an interesting subject for further investigation into its pharmacological properties and potential therapeutic applications.
Used in Drug Design and Synthesis:
(4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one is employed in drug design and synthesis as a starting point for developing new antifungal agents. Its unique structure and biological activity provide a foundation for the creation of novel compounds with improved efficacy, selectivity, and reduced side effects.
Used in Agricultural Industry:
In the agricultural industry, (4S,5R)-4-(2,4-dichlorophenyl)-5-phenyl-4-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-2-one may be used as a component in the development of antifungal agents for the protection of crops from fungal diseases. Its application in this context aims to improve crop yield and quality by reducing the impact of fungal infections on plants.

Upstream product

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Relevant articles and documents

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